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Olmesartan medoxomil
Known as:
1H-Imidazole-5-carboxylic Acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester
, 5-Methyl-2-oxo-1,3-dioxolen-4-yl)methoxy-4-(1-hydroxy-1-methylethyl)-2-propyl-1-(4-(2-(tetrazol-5-yl)phenyl)phenyl)methylimidazol-5-carboxylate - T287346
, Olmesartan Medoxomil [Chemical/Ingredient]
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A synthetic imidazole derivative prodrug with an antihypertensive property. Upon hydrolysis, olmesartan medoxomil is converted to olmesartan…
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National Institutes of Health
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Related topics
Related topics
30 relations
Amlodipine 10 MG / Hydrochlorothiazide 25 MG / Olmesartan medoxomil 40 MG Oral Tablet
Amlodipine 10 MG / Hydrochlorothiazide 25 MG / Olmesartan medoxomil 40 MG Oral Tablet [Tribenzor]
Amlodipine 5 MG / Olmesartan medoxomil 40 MG Oral Tablet [Azor]
Angiotensin 2 Receptor Antagonists [MoA]
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Broader (3)
Angiotensin II Type 1 Receptor Blockers
Antihypertensive Agents
olmesartan
Narrower (5)
Azor
Benicar
CS 866
Tribenzor
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
QbD-driven development and evaluation of nanostructured lipid carriers (NLCs) of Olmesartan medoxomil employing multivariate statistical techniques
S. Beg
,
Sumant Saini
,
Shantanu Bandopadhyay
,
O. Katare
,
Bhupinder Singh
Drug Development and Industrial Pharmacy
2018
Corpus ID: 205564727
Abstract Purpose: This research work entails quality by design (QbD)-based systematic development of nanostructured lipid…
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Highly Cited
2018
Highly Cited
2018
Development of olmesartan medoxomil lipid-based nanoparticles and nanosuspension: preparation, characterization and comparative pharmacokinetic evaluation
A. B
,
N. D.
,
Kishan Veerabrahma
Artificial Cells Nanomedicine and Biotechnology
2018
Corpus ID: 19711234
Abstract The aim was to enhance the oral bioavailability of olmesartan medoxomil (OM) by preparing solid lipid nanoparticles…
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Highly Cited
2017
Highly Cited
2017
Nanostructured lipid carriers of olmesartan medoxomil with enhanced oral bioavailability.
Vikram Kaithwas
,
C. Dora
,
Varun Kushwah
,
Sanyog Jain
Colloids and Surfaces B: Biointerfaces
2017
Corpus ID: 13421251
Highly Cited
2014
Highly Cited
2014
Nanoemulsion strategy for olmesartan medoxomil improves oral absorption and extended antihypertensive activity in hypertensive rats.
B. Gorain
,
H. Choudhury
,
+4 authors
T. Pal
Colloids and Surfaces B: Biointerfaces
2014
Corpus ID: 9994937
Highly Cited
2012
Highly Cited
2012
Development of a novel 96-microwell assay with high throughput for determination of olmesartan medoxomil in its tablets
I. Darwish
,
Tanveer A. Wani
,
N. Khalil
,
A. Al-Shaikh
,
Najm Al-Morshadi
Chemistry Central Journal
2012
Corpus ID: 1491327
A novel 96-microwell-based spectrophotometric assay has been developed and validated for determination of olmesartan medoxomil…
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Highly Cited
2011
Highly Cited
2011
Effects of the Angiotensin Receptor Blocker Azilsartan Medoxomil Versus Olmesartan and Valsartan on Ambulatory and Clinic Blood Pressure in Patients With Stages 1 and 2 Hypertension
W. White
,
M. Weber
,
+4 authors
S. Kupfer
HYPERTENSION
2011
Corpus ID: 14959388
Azilsartan medoxomil is an angiotensin receptor blocker (ARB) being developed for hypertension treatment. To compare this ARB…
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Highly Cited
2010
Highly Cited
2010
Angiotensin II-Antagonist in Paroxysmal Atrial Fibrillation (ANTIPAF)-Trial Running title: Goette et al.; The ANTIPAF Trial
A. Goette
,
N. Schön
,
+7 authors
T. Meinertz
2010
Corpus ID: 1018508
University Hospital Magdeburg, Magdeburg; Dept of Cardiology & Intensive Care Med, St. Vincenz-Hospital Paderborn, Paderborn…
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2009
2009
Solubilized formulation of olmesartan medoxomil for enhancing oral bioavailability
B. Lee
,
M. Kang
,
+5 authors
Y. Choi
Archives of pharmacal research
2009
Corpus ID: 21305212
Olmesartan medoxomil (OLM) is an antihypertensive angiotensin II receptor blocker. OLM has a low bioavailability (BA…
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Highly Cited
2009
Highly Cited
2009
Effects of olmesartan, an angiotensin II receptor blocker, and amlodipine, a calcium channel blocker, on Cardio-Ankle Vascular Index (CAVI) in type 2 diabetic patients with hypertension.
Y. Miyashita
,
A. Saiki
,
+7 authors
K. Shirai
Journal of atherosclerosis and thrombosis
2009
Corpus ID: 30774407
AIM Recently, a novel device for measuring the cardio-ankle vascular index (CAVI) as an arterial stiffness parameter has been…
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Review
2002
Review
2002
Use of angiotensin II receptor blockers in animal models of atherosclerosis.
C. Ferrario
American Journal of Hypertension
2002
Corpus ID: 7519235
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