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Reactive astrocytes are strongly induced by central nervous system (CNS) injury and disease, but their role is poorly understood… Expand Cellular diversity in the brain revealed The mammalian brain has an extraordinarily large number of cells. Although there are… Expand The major cell classes of the brain differ in their developmental processes, metabolism, signaling, and function. To better… Expand Oligodendroglia support axon survival and function through mechanisms independent of myelination, and their dysfunction leads to… Expand To realize the therapeutic potential of RNA drugs, efficient, tissue-specific and nonimmunogenic delivery technologies must be… Expand Understanding the cell–cell interactions that control CNS development and function has long been limited by the lack of methods… Expand The peroxisome proliferator-activated receptors (PPARs) are a group of three nuclear receptor isoforms, PPAR gamma, PPAR alpha… Expand Multiple sclerosis (MS) is a disease with profound heterogeneity in clinical course, neuroradiological appearance of the lesions… Expand We have identified a cell type in 7-day-old rat optic nerve that differentiates into a fibrous astrocyte if cultured in the… Expand A novel method has been developed for the preparation of nearly pure separate cultures of astrocytes and oligodendrocytes. The… Expand