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ORG 5222

Known as: ORG-5222 
National Institutes of Health

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2 relations

Broader (1)

Asenapine
asenapine maleate

Papers overview

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2001
2001
Agonist, antagonist, and inverse agonist properties of antipsychotics at human recombinant 5-HT(1A) receptors expressed in HeLa cells.
2000
2000
The effects of antipsychotics with 5-HT(2C) receptor affinity in behavioral assays selective for 5-HT(2C) receptor antagonist properties of compounds.
1998
1998
[Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum].
We examined the modulatory effect of serotonergic activities on haloperidol-induced up-regulation of dopamine D2 receptors in rat… 
1995
1995
The olfactory tubercle as a site of action of neuroleptics with an atypical profile in the paw test: effect of risperidone, prothipendyl, ORG 5222, sertindole and olanzapine
The paw test was used to detect the preclinical profile (classical versus atypical) of five putative, atypical neuroleptics… 
1993
1993
[A study on the pharmacological properties of atypical antipsychotic drugs: in vivo dopamine and serotonin receptor occupancy by atypical antipsychotic drugs in the rat brain].
In vivo occupancy by typical or atypical antipsychotic drugs of dopamine D-1, D-2 and serotonin (5-HT)2 receptors in the… 
1992
1992
ORG 5222, AN ANTIPSYCHOTIC WITH POTENT 5‐HT RECEPTOR BINDING IN ANIMALS.
1992
1992
PHASE I STUDY OF ORG 5222, AN ANTIPSYCHOTIC WITH ANTAGONISM FOR SEROTONIN 2 AND DOPAMINE ‐D1, ‐D2
1991
1991
The effect of the potential antipsychotic ORG 5222 on local cerebral glucose utilization in freely moving rats.
1990
1990
Behavioural pharmacology of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro- 1H-dibenz[2,3:6,7]oxepino-[4,5-c]pyrrolidine maleate, a compound interacting with dopaminergic and serotonergic receptors.
trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H- dibenz[2,3:6,7]oxepinol[4,5-c]pyrrolidine maleate (Org 5222) is a new compound… 
1990
1990
Physico-chemical properties and stability of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H- dibenz[2,3:6,7]oxepino[4,5-c]pyrrolidine maleate.
The physico-chemical properties of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H- dibenz[2,3:6,7]oxepino[4,5-c]pyrrolidine… 
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