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ORG 5222
Known as:
ORG-5222
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Asenapine
asenapine maleate
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds.
E. Richelson
,
T. Souder
Life Science
2000
Corpus ID: 35159479
2000
2000
The effects of antipsychotics with 5-HT(2C) receptor affinity in behavioral assays selective for 5-HT(2C) receptor antagonist properties of compounds.
E. Prinssen
,
W. Koek
,
M. Kleven
European Journal of Pharmacology
2000
Corpus ID: 5963385
1998
1998
[Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum].
T. Ishikane
[Hokkaido igaku zasshi] The Hokkaido journal of…
1998
Corpus ID: 24071523
We examined the modulatory effect of serotonergic activities on haloperidol-induced up-regulation of dopamine D2 receptors in rat…
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1997
1997
Effects of serotonergic agents on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum.
T. Ishikane
,
I. Kusumi
,
R. Matsubara
,
S. Matsubara
,
T. Koyama
European Journal of Pharmacology
1997
Corpus ID: 25027966
1997
1997
Central 5-HT2A and D2 dopamine receptor occupancy after sublingual administration of ORG 5222 in healthy men
B. Andrée
,
C. Halldin
,
M. V. Vries
,
L. Farde
Psychopharmacology
1997
Corpus ID: 21253110
Abstract It has been suggested that a combined blockade of 5-HT2A and D2-dopamine receptors improves efficacy and reduces the…
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Highly Cited
1996
Highly Cited
1996
Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding
A. Schotte
,
P. Janssen
,
+5 authors
J. Leysen
Psychopharmacology
1996
Corpus ID: 12028979
Risperidone and its active metabolite 9-OH-risperidone were compared to reference antipsychotic drugs (haloperidol, pipamperone…
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1995
1995
The olfactory tubercle as a site of action of neuroleptics with an atypical profile in the paw test: effect of risperidone, prothipendyl, ORG 5222, sertindole and olanzapine
A. Cools
,
E. Prinssen
,
B. Ellenbroek
Psychopharmacology
1995
Corpus ID: 26438435
The paw test was used to detect the preclinical profile (classical versus atypical) of five putative, atypical neuroleptics…
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Highly Cited
1993
Highly Cited
1993
Dopamine D1, D2 and serotonin2 receptor occupation by typical and atypical antipsychotic drugs in vivo.
S. Matsubara
,
R. Matsubara
,
I. Kusumi
,
T. Koyama
,
I. Yamashita
Journal of Pharmacology and Experimental…
1993
Corpus ID: 9147164
In vivo occupation of dopamine D1 and D2 and serotonin (5-HT)2 receptors by typical and atypical antipsychotic drugs (APD) was…
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1991
1991
The effect of the potential antipsychotic ORG 5222 on local cerebral glucose utilization in freely moving rats.
P. Room
,
A. Tielemans
,
T. de Boer
,
A. V. van Delft
,
J. Tonnaer
European Journal of Pharmacology
1991
Corpus ID: 42497719
1990
1990
Actions of ORG 5222 as a novel psychotropic agent
B. Costall
,
A. Domeney
,
M. Kelly
,
R. Naylor
,
D. Tomkins
Pharmacology, Biochemistry and Behavior
1990
Corpus ID: 21423909
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