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ORG 5222

Known as: ORG-5222 
National Institutes of Health

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2 relations

Broader (1)

Asenapine
asenapine maleate

Papers overview

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Highly Cited
2000
Highly Cited
2000
Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds.
2000
2000
The effects of antipsychotics with 5-HT(2C) receptor affinity in behavioral assays selective for 5-HT(2C) receptor antagonist properties of compounds.
1998
1998
[Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum].
  • T. Ishikane
  • [Hokkaido igaku zasshi] The Hokkaido journal of…
  • 1998
  • Corpus ID: 24071523
We examined the modulatory effect of serotonergic activities on haloperidol-induced up-regulation of dopamine D2 receptors in rat… 
1997
1997
Effects of serotonergic agents on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum.
1997
1997
Central 5-HT2A and D2 dopamine receptor occupancy after sublingual administration of ORG 5222 in healthy men
Abstract It has been suggested that a combined blockade of 5-HT2A and D2-dopamine receptors improves efficacy and reduces the… 
Highly Cited
1996
Highly Cited
1996
Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding
Risperidone and its active metabolite 9-OH-risperidone were compared to reference antipsychotic drugs (haloperidol, pipamperone… 
1995
1995
The olfactory tubercle as a site of action of neuroleptics with an atypical profile in the paw test: effect of risperidone, prothipendyl, ORG 5222, sertindole and olanzapine
The paw test was used to detect the preclinical profile (classical versus atypical) of five putative, atypical neuroleptics… 
Highly Cited
1993
Highly Cited
1993
Dopamine D1, D2 and serotonin2 receptor occupation by typical and atypical antipsychotic drugs in vivo.
In vivo occupation of dopamine D1 and D2 and serotonin (5-HT)2 receptors by typical and atypical antipsychotic drugs (APD) was… 
1991
1991
The effect of the potential antipsychotic ORG 5222 on local cerebral glucose utilization in freely moving rats.
1990
1990
Actions of ORG 5222 as a novel psychotropic agent
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