Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

ORG 5222

Known as: ORG-5222 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Risperidone and its active metabolite 9-OH-risperidone were compared to reference antipsychotic drugs (haloperidol, pipamperone… Expand
  • figure 1
  • table 1
  • table 1
  • table 2
  • table 3
Is this relevant?
2005
2005
The paw test was used to detect the preclinical profile (classical versus atypical) of five putative, atypical neuroleptics… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Using radioligand binding assays and post-mortem normal human brain tissue, we obtained equilibrium dissociation constants (K(d)s… Expand
Is this relevant?
2000
2000
Many antipsychotics have marked antagonist effects at 5-hydroxytryptamine (5-HT(2C)) receptors in vitro, which, however, have… Expand
Is this relevant?
1998
1998
  • T. Ishikane
  • [Hokkaido igaku zasshi] The Hokkaido journal of…
  • 1998
  • Corpus ID: 24071523
We examined the modulatory effect of serotonergic activities on haloperidol-induced up-regulation of dopamine D2 receptors in rat… Expand
Is this relevant?
1997
1997
Abstract It has been suggested that a combined blockade of 5-HT2A and D2-dopamine receptors improves efficacy and reduces the… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 5
Is this relevant?
1997
1997
We examined the modulatory effect of serotonergic activities on haloperidol-induced up-regulation of dopamine D2 receptors in rat… Expand
Is this relevant?
1993
1993
In vivo occupation of dopamine D1 and D2 and serotonin (5-HT)2 receptors by typical and atypical antipsychotic drugs (APD) was… Expand
Is this relevant?
1991
1991
The effects of administration of different doses of the potential antipsychotic Org 5222 (0.01 and 0.1 mg/kg i.v.) upon local… Expand
Is this relevant?
1990
1990
ORG 5222 is a tetracyclic compound with high affinity for dopamine and 5-HT2 receptors. ORG 5222 was compared to fluphenazine in… Expand
Is this relevant?