Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

ORG 5222

Known as: ORG-5222 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Risperidone and its active metabolite 9-OH-risperidone were compared to reference antipsychotic drugs (haloperidol, pipamperone… Expand
  • figure 1
  • table 1
  • table 1
  • table 2
  • table 3
2005
2005
The paw test was used to detect the preclinical profile (classical versus atypical) of five putative, atypical neuroleptics… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
2000
Highly Cited
2000
Using radioligand binding assays and post-mortem normal human brain tissue, we obtained equilibrium dissociation constants (K(d)s… Expand
2000
2000
Many antipsychotics have marked antagonist effects at 5-hydroxytryptamine (5-HT(2C)) receptors in vitro, which, however, have… Expand
1998
1998
  • T. Ishikane
  • [Hokkaido igaku zasshi] The Hokkaido journal of…
  • 1998
  • Corpus ID: 24071523
We examined the modulatory effect of serotonergic activities on haloperidol-induced up-regulation of dopamine D2 receptors in rat… Expand
1997
1997
Abstract It has been suggested that a combined blockade of 5-HT2A and D2-dopamine receptors improves efficacy and reduces the… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 5
1997
1997
We examined the modulatory effect of serotonergic activities on haloperidol-induced up-regulation of dopamine D2 receptors in rat… Expand
Highly Cited
1993
Highly Cited
1993
In vivo occupation of dopamine D1 and D2 and serotonin (5-HT)2 receptors by typical and atypical antipsychotic drugs (APD) was… Expand
1991
1991
The effects of administration of different doses of the potential antipsychotic Org 5222 (0.01 and 0.1 mg/kg i.v.) upon local… Expand
1990
1990
ORG 5222 is a tetracyclic compound with high affinity for dopamine and 5-HT2 receptors. ORG 5222 was compared to fluphenazine in… Expand