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OPTC gene

Known as: OPTC, OPTICIN, oculoglycan 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Characterization of opticin digestion by proteases involved in osteoarthritis development.
2012
2012
Opticin Exerts Its Anti-angiogenic Activity by Regulating Extracellular Matrix Adhesiveness
Background: Recently, we demonstrated that the glycoprotein opticin is anti-angiogenic. Here, the underpining mechanism is… 
2012
2012
Opticin production is reduced by hypoxia and VEGF in human retinal pigment epithelium via MMP-2 activation.
2008
2008
Identification of opticin, a member of the small leucine-rich repeat proteoglycan family, in human articular tissues: a novel target for MMP-13 in osteoarthritis.
2006
2006
Neoplastic transformation of ciliary body epithelium is associated with loss of opticin expression
Background: Opticin is a recently discovered glycoprotein present predominantly in the vitreous humour. It is synthesised and… 
2004
2004
The expression pattern of opticin during chicken embryogenesis.
Highly Cited
2003
Highly Cited
2003
Opticin binds retinal growth hormone in the embryonic vitreous.
PURPOSE Opticin is a small leucine-rich repeat proteoglycan that is abundant in several ocular tissues, including the vitreous… 
2003
2003
Characterization of Opticin and Evidence of Stable Dimerization in Solution*
Opticin is a class III member of the extracellular matrix small leucine-rich repeat protein (SLRP) family that was initially… 
Highly Cited
2001
Highly Cited
2001
Structure, chromosomal location, and tissue-specific expression of the mouse opticin gene.
PURPOSE To determine the structure, location, and tissue-specific expression of the mouse opticin gene (Optc) and to compare… 
2000
2000
Cloning, modeling, and chromosomal localization for a small leucine-rich repeat proteoglycan (SLRP) family member expressed in human eye.
PURPOSE To examine a highly abundant novel transcript from human iris. METHODS Expressed sequence tag (EST) analysis of an… 
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