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ONO 6818
Known as:
ONO-6818
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Oxadiazoles
Pyrimidinones
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Pathophysiological studies of trinitrobenzene sulfonic acid-induced colitis in Syrian hamsters (Mesocricetus auratus).
Yasushi Hirota
,
Mikie Suzuki
,
K. Yamaguchi
,
T. Fujita
,
N. Katsube
Comparative medicine
2005
Corpus ID: 39106788
We developed a colitis model in Syrian hamsters (Mesocricetus auratus) to investigate the relationship between colitis and…
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2004
2004
Effects of the neutrophil elastase inhibitor (ONO-6818) on acetic acid induced colitis in Syrian hamsters.
Yasushi Hirota
,
Mikie Suzuki
,
K. Yamaguchi
,
T. Fujita
,
N. Katsube
Journal of Veterinary Medical Science
2004
Corpus ID: 13035330
Neutrophil elastase (NE) released from neutrophils during inflammation is related to tissue disturbance and organ failure. We…
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2004
2004
1064-178 A novel oral neutrophil elastase inhibitor, ONO-6818, suppressed early atherosclerotic plaque formation in apolipoprotein E-knockout mice
Y. Iso
,
Hiroshi Suzuki
,
+6 authors
Takashi Katagoro
2004
Corpus ID: 71675124
2003
2003
ONO-6818, a novel, potent neutrophil elastase inhibitor, reduces inflammatory mediators during simulated extracorporeal circulation.
Y. Yoshimura
,
Y. Hiramatsu
,
+4 authors
Y. Sakakibara
Annals of Thoracic Surgery
2003
Corpus ID: 23910938
Highly Cited
2002
Highly Cited
2002
A novel oral neutrophil elastase inhibitor (ONO-6818) inhibits human neutrophil elastase-induced emphysema in rats.
T. Kuraki
,
M. Ishibashi
,
M. Takayama
,
M. Shiraishi
,
Minoru Yoshida
American Journal of Respiratory and Critical Care…
2002
Corpus ID: 35010932
We investigated the effects of a novel oral neutrophil elastase inhibitor (ONO-6818) on acute lung injury and pulmonary emphysema…
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Review
2002
Review
2002
ONO-6818 Cortech/Ono.
Alexandre Trifilieff
Current opinion in investigational drugs
2002
Corpus ID: 31865961
ONO-6818 (CP-955) is the lead compound in a series of orally bioavailable neutrophil elastase inhibitors licensed from Cortech…
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2001
2001
A novel oral neutrophil elastase inhibitor (ONO-6818) inhibits human neutrophil elastase-induced emphysema in rats
隆繁 久良木
2001
Corpus ID: 88463153
2001
2001
Production and pharmacologic modulation of the granulocyte-associated allergic responses to ovalbumin in murine skin models induced by injecting ovalbumin-specific Th1 or Th2 cells.
T. Terui
,
K. Sano
,
+6 authors
H. Tagami
Journal of Investigative Dermatology
2001
Corpus ID: 9001933
Because interferon-gamma, interleukin-4, and interleukin-5 have been identified at the mRNA and protein levels in the lesional…
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2001
2001
Design and synthesis of new orally active inhibitors of human neutrophil elastase.
K. Ohmoto
,
M. Okuma
,
+10 authors
M. Toda
Bioorganic & Medicinal Chemistry
2001
Corpus ID: 29709590
2001
2001
The crystal structure of the complex of non-peptidic inhibitor of human neutrophil elastase ONO-6818 and porcine pancreatic elastase.
Y. Odagaki
,
K. Ohmoto
,
+4 authors
Y. Katsuya
Bioorganic & Medicinal Chemistry
2001
Corpus ID: 39393853
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