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ONO 2235

Known as: ONO-2235 
National Institutes of Health

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epalrestat

Papers overview

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1996
1996
Restoration of nitric oxide production by aldose reductase inhibitor in human endothelial cells cultured in high-glucose medium.
1993
1993
A Placebo‐controlled Double‐blind Study of Epalrestat (ONO‐2235) in Patients with Diabetic Neuropathy
‘Department of lnternal Medicine, Tohoku Kosei-Nenkin Hospital bThe Third Department of Internal Medicine and ‘The Neurological… 
1991
1991
Effects of aldose reductase inhibitors on prostacyclin (PGI2) synthesis by aortic rings from rats with streptozotocin-induced diabetes.
1991
1991
Properties of novel aldose reductase inhibitors, M16209 and M16287, in comparison with known inhibitors, ONO-2235 and sorbinil.
Properties and efficacies of novel aldose reductase (AR) inhibitors, M16209 (1-(3-bromobenzo[b]furan-2-ylsulfonyl)hydantoin) and… 
Highly Cited
1990
Highly Cited
1990
Isoliquiritigenin: a new aldose reductase inhibitor from glycyrrhizae radix.
Traditionally in Japan, some kampo medicines (traditional oriental herbal prescriptions) have long been used for the treatment of… 
1989
1989
In vitro motor activity of intestinal segments of streptozotocin diabetic rats.
1985
1985
Effects of a fructose-rich diet and the aldose reductase inhibitor, ONO-2235, on the development of diabetic neuropathy in streptozotocin-treated rats
SummaryStreptozotocin-diabetic rats were maintained on a 72% fructose diet for 4 weeks and some were treated with an aldose… 
1984
1984
Prevention of peripheral nerve dysfunction by an aldose reductase inhibitor in streptozotocin-diabetic rats.
Highly Cited
1984
Highly Cited
1984
Effects of a new aldose reductase inhibitor on various tissues in vitro.
A new aldose reductase inhibitor, ONO-2235 [(E)-3-carboxymethyl-5-[(2E)-methyl-3-phenylpropenylidene] rhodanine], was found to… 
1983
1983
Effect of a new aldose reductase inhibitor, (E)-3-carboxymethyl-5-[(2E)-methyl-3-phenylpropenylidene]rhodanine (ONO-2235) on peripheral nerve disorders in streptozotocin-diabetic rats
SummaryA new aldose reductase inhibitor, (E)-3-carboxy-methyl-5-[(2E-methyl-3-phenylpropenylidene]rhodanine (ONO-2235) was… 
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