epalrestat

Known as: 3-carboxymethyl-5-(methyl-3-phenylpropenylidene)rhodanine, 3-thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (E,E)- 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
024619902018

Papers overview

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2011
2011
AIM OF THE STUDY To investigate the effects of lignans extracted from Eucommia ulmoides and epalrestat on vascular remodeling in… (More)
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2009
2009
The increased flux of polyol pathway induced by hyperglycemia is implicated in the pathogenesis of various complications… (More)
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2008
2008
BACKGROUND A number of diabetic patients with diabetic neuropathy, in India, were treated with epalrestat, an aldose reductase… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE We sought to evaluate the long-term efficacy and safety of epalrestat, an aldose reductase inhibitor, on diabetic… (More)
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2003
2003
OBJECTIVE Diabetic patients with severe autonomic nervous disorder show delayed gastric emptying accompanied by diabetic… (More)
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2001
2001
The aim of the present study was to elucidate the long-term effect of epalrestat, an aldose reductase inhibitor (ARI), on renal… (More)
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2000
2000
OBJECTIVE To clarify the role of the polyol pathway in the intracellular formation of advanced glycation end products in human… (More)
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1999
1999
To evaluate the effect of long-term administration of an aldose reductase inhibitor on diabetic cardiovascular autonomic… (More)
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1996
1996
A number of diabetic patients with diabetic neuropathy were treated with epalrestat, an aldose reductase inhibitor, since this… (More)
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1994
1994
In order to clarify the possible contribution of the abnormal polyol pathway to the development of diabetic nephropathy, the… (More)
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