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ODC1 gene

Known as: ODC1, ODC, ORNITHINE DECARBOXYLASE 2 
This gene plays a role in ornithine metabolism.
National Institutes of Health

Related topics

Related topics

4 relations
Biogenic Amine Metabolic ProcessODCP geneOrnithine Decarboxylase

Narrower (1)

ODC1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Physiological importance of polyamines
Summary Polyamines are polycationic molecules that contain two or more amino groups (–NH3 +) and are present in all eukaryotic… 
Highly Cited
2017
Highly Cited
2017
The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription.
Myc oncoproteins exert tumorigenic effects by regulating expression of target oncogenes. Histone H3 lysine 79 (H3K79) methylation… 
Highly Cited
2013
Highly Cited
2013
Glutamatergic GRIN2B and polyaminergic ODC1 genes in suicide attempts: associations and gene–environment interactions with childhood/adolescent physical assault
The complex etiology of suicidal behavior has frequently been investigated in relation to monoaminergic neurotransmission, but… 
Highly Cited
2013
Highly Cited
2013
Dissecting Rice Polyamine Metabolism under Controlled Long-Term Drought Stress
A selection of 21 rice cultivars (Oryza sativa L. ssp. indica and japonica) was characterized under moderate long-term drought… 
2012
2012
Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma
Polyamines are highly regulated essential cations that are elevated in rapidly proliferating tissues, including diverse cancers… 
Review
2012
Review
2012
A role for polyamine regulators in ESC self-renewal
Embryonic stem cells (ESCs) depend on extensive regulatory networks to coordinate their self-renewal and differentiation. The… 
Highly Cited
2008
Highly Cited
2008
ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma.
Neuroblastoma is a frequently lethal childhood tumor in which MYC gene deregulation, commonly as MYCN amplification, portends… 
Review
2008
Review
2008
A review of gene-drug interactions for nonsteroidal anti-inflammatory drug use in preventing colorectal neoplasia
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to be effective chemopreventive agents for colorectal neoplasia… 
2003
2003
Transcriptional profiling of medulloblastoma in children.
OBJECT Although medulloblastoma is the most common malignant brain tumor found in children, little is known about its molecular… 
1994
1994
Complex interactions at a GC-rich domain regulate cell type-dependent activity of the ornithine decarboxylase promoter.
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