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Nucleoside Deaminases

Known as: Deaminases, Nucleoside, Nucleoside Deaminases [Chemical/Ingredient], nucleoside deaminase 
Catalyze the hydrolysis of nucleosides with the elimination of ammonia.
National Institutes of Health

Related topics

Related topics

10 relations

Broader (1)

Aminohydrolases
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Narrower (2)

S-adenosylhomocysteine deaminaseguanosine deaminase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1991
Review
1991
The measurement of nucleoside deaminases by high performance liquid chromatography and their use in clinical chemistry.
The measurement of the nucleoside deaminases--cytidine deaminase, guanosine deaminase and adenosine deaminase--by reversed phase… 
1979
1979
Phase I evaluation of tetrahydrouridine combined with cytosine arabinoside.
In conventional clinical use, cytosine arabinoside (ara-C) is rapidly deaminated by pyrimidine nucleoside deaminase to the… 
1978
1978
Deoxycytidine kinase and cytosine nucleoside deaminase activities in synchronized cultures of normal rat kidney cells.
Previous work has suggested that 1-beta-D-arabinofuranosylcytosine 5'-triphosphate is the active metabolite of 1-beta-D… 
Review
1977
Review
1977
The mechanisms of lethal action of arabinosyl cytosine (araC) and arabinosyl adenine (araA)
Certain D‐arabinosyl nucleosides, notably arabinosyl cytosine (araC) and arabinosyl adenine (araA), are useful in the treatment… 
1976
1976
Correlation analysis of Baker's studies on enzyme inhibition. 2. Chymotrypsin, trypsin, thymidine phosphorylase, uridine phosphorylase, thymidylate synthetase, cytosine nucleoside deaminase…
The inhibitory activity of 1058 inhibitors of the title enzymes has been formulated in 13 equations correlating chemical… 
1973
1973
Studies on nucleoside deaminase. Increase in activity in HeLa cell cultures caused by cytosine arabinoside.
Abstract Cytosine arabinoside (ara-C) is metabolized via two enzymatic pathways: by phosphorylation to the nucleoside… 
1969
1969
Studies on drug resistance. I. Distribution of l-beta-D-arabinofuranosylcytosine, cytidine and deoxycytidine in mice bearing ara-C-sensitive and-resistant P815 neoplasms.
1965
1965
Enzymes from insect tissues which catabolize pyrimidine compounds.
Highly Cited
1963
Highly Cited
1963
Studies on the metabolism of 5-iodo-2'-deoxycytidine in vitro. Purification of nucleoside deaminase from mouse kidney.
Highly Cited
1961
Highly Cited
1961
Nucleotide interconversions. IV. Activities of deoxycytidylate deaminase and thymidylate synthetase in normal rat liver and hepatomas.
Normal and neoplastic rat liver was analyzed for deoxycytidylate deaminase and thymidylate synthetase. For these assays, highly… 
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