Nuclear Reprogramming

Known as: Reprogramming, Nuclear 
The process that reverts CELL NUCLEI of fully differentiated somatic cells to a pluripotent or totipotent state.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Retroviral overexpression of reprogramming factors (Oct4, Sox2, Klf4, c-Myc) generates induced pluripotent stem cells (iPSCs… (More)
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Highly Cited
2011
Highly Cited
2011
The bioenergetics of somatic dedifferentiation into induced pluripotent stem cells remains largely unknown. Here, stemness factor… (More)
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Highly Cited
2011
Highly Cited
2011
Sperm and eggs carry distinctive epigenetic modifications that are adjusted by reprogramming after fertilization. The paternal… (More)
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Review
2010
Review
2010
The stable states of differentiated cells are now known to be controlled by dynamic mechanisms that can easily be perturbed. An… (More)
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Highly Cited
2010
Highly Cited
2010
Reprogramming of somatic cell nuclei to yield induced pluripotent stem (iPS) cells makes possible derivation of patient-specific… (More)
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Highly Cited
2009
Highly Cited
2009
Current DNA methylation assays are limited in the flexibility and efficiency of characterizing a large number of genomic targets… (More)
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Highly Cited
2008
Highly Cited
2008
Ectopic expression of the transcription factors Oct4, Sox2, c-Myc, and Klf4 in fibroblasts generates induced pluripotent stem… (More)
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Review
2008
Review
2008
Nuclear reprogramming describes a switch in gene expression of one kind of cell to that of another unrelated cell type. Early… (More)
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Highly Cited
2007
Highly Cited
2007
Ectopic expression of the four transcription factors Oct4, Sox2, c-Myc, and Klf4 is sufficient to confer a pluripotent state upon… (More)
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Highly Cited
2001
Highly Cited
2001
The resetting of a somatic epigenotype to a totipotential state has been demonstrated by successful animal cloning, via… (More)
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