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Nuclear Receptor Coactivators

Known as: Nuclear Receptor Coactivators [Chemical/Ingredient] 
Proteins that enhance gene expression when associated with ligand bound activated NUCLEAR RECEPTORS. The coactivators may act through an enzymatic… Expand
National Institutes of Health

Related topics

Related topics

14 relations
In BloodProcess of secretionagonistsantagonists & inhibitors
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Narrower (6)

NCOA4 protein, humanNCOA6 protein, humanNcoa6 protein, ratPpargc1b protein, rat
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
The Hippo Pathway: Biology and Pathophysiology.
The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an… Expand
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Highly Cited
2002
Highly Cited
2002
Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators
Nuclear hormone receptors are ligand-activated transcription factors that regulate the expression of genes that are essential for… Expand
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Review
2000
Review
2000
Acetylation of Histones and Transcription-Related Factors
SUMMARY The state of chromatin (the packaging of DNA in eukaryotes) has long been recognized to have major effects on levels of… Expand
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Highly Cited
2000
Highly Cited
2000
Mouse Zac1, a Transcriptional Coactivator and Repressor for Nuclear Receptors
ABSTRACT Transcriptional activation by nuclear hormone receptors is mediated by the 160-kDa family of nuclear receptor… Expand
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Highly Cited
2000
Highly Cited
2000
The DRIP Complex and SRC-1/p160 Coactivators Share Similar Nuclear Receptor Binding Determinants but Constitute Functionally Distinct Complexes
ABSTRACT Transcriptional activation requires both access to DNA assembled as chromatin and functional contact with components of… Expand
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Review
1999
Review
1999
Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functionsProceedings of Xth International Congress on Hormonal Steroids, Quebec, Canada, 17–21 June 1998.
Nuclear receptors are ligand-inducible transcription factors which mediate the physiological effects of steroid, thyroid and… Expand
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Highly Cited
1998
Highly Cited
1998
Transcription factor-specific requirements for coactivators and their acetyltransferase functions.
Different classes of mammalian transcription factors-nuclear receptors, cyclic adenosine 3',5'-monophosphate-regulated enhancer… Expand
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Review
1997
Review
1997
Physiological action of progesterone in target tissues.
I. Introduction II. Synthesis and Secretion of Progesterone III. The Progesterone Receptor A. PR expression and regulation IV… Expand
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Highly Cited
1997
Highly Cited
1997
Interaction between the Amino- and Carboxyl-terminal Regions of the Rat Androgen Receptor Modulates Transcriptional Activity and Is Influenced by Nuclear Receptor Coactivators*
Identical N-terminal deletions in the wild-type rat androgen receptor (rAR) and a constitutively active rAR (ARΔ641–902) devoid… Expand
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Highly Cited
1996
Highly Cited
1996
A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors
Nuclear receptors regulate gene expression by direct activation of target genes and inhibition of AP-1. Here we report that… Expand
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