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Nuclear Localization Signals

Known as: NLS Peptide, Nuclear Localization Signal Peptide, Nuclear Localization Signals [Chemical/Ingredient] 
Short, predominantly basic amino acid sequences identified as nuclear import signals for some proteins. These sequences are believed to interact with… 
National Institutes of Health

Related topics

Related topics

25 relations
BRCA1 protein, humanDAXX protein, humanFABP4 protein, humanIFI16 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1998
Highly Cited
1998
Nuclear Localization Signal Receptor Importin α Associates with the Cytoskeleton
Importin α is the nuclear localization signal (NLS) receptor that is involved in the nuclear import of proteins containing basic… 
Highly Cited
1996
Highly Cited
1996
Functional domains of the transcription factor USF2: atypical nuclear localization signals and context-dependent transcriptional activation domains
USF is a family of basic helix-loop transcriptional factors that recognizes DNA-binding sites similar to those of the Myc… 
Highly Cited
1995
Highly Cited
1995
Arginine-rich regions succeeding the nuclear localization region of the herpes simplex virus type 1 regulatory protein ICP27 are required for efficient nuclear localization and late gene expression
The herpes simplex virus type 1 (HSV-1) immediate-early protein ICP27 is an essential regulatory protein that localizes to the… 
Highly Cited
1994
Highly Cited
1994
Nuclear localization signals also mediate the outward movement of proteins from the nucleus.
Several nuclear proteins, including steroid hormone receptors, have been shown to shuttle continuously between the nucleus and… 
Highly Cited
1992
Highly Cited
1992
Interferon-induced Mx proteins form oligomers and contain a putative leucine zipper.
Highly Cited
1992
Highly Cited
1992
Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function.
Highly Cited
1990
Highly Cited
1990
An N-ethylmaleimide-sensitive cytosolic factor necessary for nuclear protein import: requirement in signal-mediated binding to the nuclear pore
We described previously an assay for authentic nuclear protein import in vitro. In this assay, exogenous nuclei are placed in an… 
Highly Cited
1988
Highly Cited
1988
Two nuclear location signals in the influenza virus NS1 nonstructural protein
The NS1 protein of influenza A virus has been shown to enter and accumulate in the nuclei of virus-infected cells independently… 
Highly Cited
1988
Highly Cited
1988
Nuclear protein import: specificity for transport across the nuclear pore.
Highly Cited
1987
Highly Cited
1987
Pentapeptide nuclear localization signal in adenovirus E1a
The adenovirus E1a gene products are nuclear proteins important in transcriptional control of viral functions during infection… 
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