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Nuclear Localization Signals
Known as:
NLS Peptide
, Nuclear Localization Signal Peptide
, Nuclear Localization Signals [Chemical/Ingredient]
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Short, predominantly basic amino acid sequences identified as nuclear import signals for some proteins. These sequences are believed to interact with…
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National Institutes of Health
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Related topics
Related topics
25 relations
BRCA1 protein, human
DAXX protein, human
FABP4 protein, human
IFI16 protein, human
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1998
Highly Cited
1998
Nuclear Localization Signal Receptor Importin α Associates with the Cytoskeleton
Harley M. Smith
,
N. Raikhel
The Plant Cell
1998
Corpus ID: 6183263
Importin α is the nuclear localization signal (NLS) receptor that is involved in the nuclear import of proteins containing basic…
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Highly Cited
1996
Highly Cited
1996
Functional domains of the transcription factor USF2: atypical nuclear localization signals and context-dependent transcriptional activation domains
Xu Luo
,
Michèle Sawadogo
Molecular and Cellular Biology
1996
Corpus ID: 162274
USF is a family of basic helix-loop transcriptional factors that recognizes DNA-binding sites similar to those of the Myc…
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Highly Cited
1995
Highly Cited
1995
Arginine-rich regions succeeding the nuclear localization region of the herpes simplex virus type 1 regulatory protein ICP27 are required for efficient nuclear localization and late gene expression
M. Hibbard
,
R. Sandri-Goldin
Journal of Virology
1995
Corpus ID: 16440806
The herpes simplex virus type 1 (HSV-1) immediate-early protein ICP27 is an essential regulatory protein that localizes to the…
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Highly Cited
1994
Highly Cited
1994
Nuclear localization signals also mediate the outward movement of proteins from the nucleus.
A. Guiochon‐Mantel
,
Karine Delabre
,
P. Lescop
,
Edwin Milgrom
Proceedings of the National Academy of Sciences…
1994
Corpus ID: 23666626
Several nuclear proteins, including steroid hormone receptors, have been shown to shuttle continuously between the nucleus and…
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Highly Cited
1992
Highly Cited
1992
Interferon-induced Mx proteins form oligomers and contain a putative leucine zipper.
K. Melén
,
T. Ronni
,
B. Broni
,
R. Krug
,
C. von Bonsdorff
,
I. Julkunen
Journal of Biological Chemistry
1992
Corpus ID: 1054898
Highly Cited
1992
Highly Cited
1992
Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function.
Jan Alsner
,
Jesper Q. Svejstrup
,
E. Kjeldsen
,
Boe Sandahl Sorensen
,
O. Westergaard
Journal of Biological Chemistry
1992
Corpus ID: 41155755
Highly Cited
1990
Highly Cited
1990
An N-ethylmaleimide-sensitive cytosolic factor necessary for nuclear protein import: requirement in signal-mediated binding to the nuclear pore
D. Newmeyer
,
D. Forbes
Journal of Cell Biology
1990
Corpus ID: 18959364
We described previously an assay for authentic nuclear protein import in vitro. In this assay, exogenous nuclei are placed in an…
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Highly Cited
1988
Highly Cited
1988
Two nuclear location signals in the influenza virus NS1 nonstructural protein
Deborah Greenspan
,
P. Palese
,
M. Krystal
Journal of Virology
1988
Corpus ID: 28855901
The NS1 protein of influenza A virus has been shown to enter and accumulate in the nuclei of virus-infected cells independently…
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Highly Cited
1988
Highly Cited
1988
Nuclear protein import: specificity for transport across the nuclear pore.
B. Wolff
,
M. Willingham
,
J. Hanover
Experimental Cell Research
1988
Corpus ID: 30908267
Highly Cited
1987
Highly Cited
1987
Pentapeptide nuclear localization signal in adenovirus E1a
R. Lyons
,
B. Ferguson
,
M. Rosenberg
Molecular and Cellular Biology
1987
Corpus ID: 25449260
The adenovirus E1a gene products are nuclear proteins important in transcriptional control of viral functions during infection…
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