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Notch

Known as: notching 
National Institutes of Health

Papers overview

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2013
2013
NOTCH knockdown affects the proliferation and mTOR signaling of leukemia cells.
AIM The effects of small interfering RNA (siRNA)-mediated knockdown of NOTCH1 and NOTCH2 on cell proliferation and downstream… 
2012
2012
Notch inhibition suppresses nasopharyngeal carcinoma by depleting cancer stem-like side population cells.
The cancer stem cell (CSC) is responsible for the initiation, proliferation and radiation resistance. Side population… 
2010
2010
NOTCH mutations as prognostic markers in T-ALL
Risk stratification plays a fundamental role in the treatment of acute lymphoblastic leukemia (ALL). Thus, patients harboring… 
2009
2009
Notch signaling and developmental cell-cycle arrest in Drosophila polar follicle cells.
Temporal and spatial regulation of cell division is critical for proper development of multicellular organisms. An important… 
Highly Cited
2008
Highly Cited
2008
Methylmercury inhibits differentiation of rat neural stem cells via Notch signalling
The Notch receptor is essential for neural stem cell (NSC) characteristics. Relatively high concentrations (micromolar) of… 
Review
2008
Review
2008
Notch and Integrin Affinity: A Sticky Situation
The Notch pathway is a conserved signal transduction system that mediates intercellular signaling to regulate cell fate decisions… 
2006
2006
Notch Signaling Is Inactive but Inducible in Human Embryonic Stem Cells
The NOTCH signaling pathway performs a wide range of critical functions in a number of different cell types during development… 
2000
2000
Notch Responds Differently to Delta and Wingless in CulturedDrosophila Cells*
Notch, a cell surface receptor, is required for producing different types of cells during development ofDrosophila melanogaster… 
Highly Cited
1997
Highly Cited
1997
Regulation of the ERBB-2 promoter by RBPJkappa and NOTCH.
Within the human ERBB-2 gene promoter, a 100-base pair region 5' to the TATA box enhances basal transcription 200-fold. Two… 
1989
1989
The expression of the neurogenic locus Notch during the postembryonic development of Drosophila melanogaster and its relationship to mitotic activity.
The molecular analysis of the Notch locus of Drosophila melanogaster demonstrated that it codes for a protein which shows… 
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