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Notch Signaling Pathway

Known as: Notch receptor signalling pathway, Notch receptor signaling pathway, Notch signalling pathway 
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending… 
National Institutes of Health

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ADAM17 protein, humanADAM17 wt AlleleBTRC wt AlleleC-Terminal Binding Protein 1

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Notch signaling pathway involved in somitogenesis

Papers overview

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Highly Cited
2018
Highly Cited
2018
Cis-activation in the Notch signaling pathway
The Notch signaling pathway consists of transmembrane ligands and receptors that can interact both within the same cell (cis) and… 
Highly Cited
2012
Highly Cited
2012
miR-210 activates notch signaling pathway in angiogenesis induced by cerebral ischemia
The compensatory angiogenesis that occurs after cerebral ischemia increases blood flow to the injured area and limits extension… 
Highly Cited
2009
Highly Cited
2009
Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway.
Despite rapid advances in many fronts, pancreatic cancer (PC) remains one of the most difficult human malignancies to treat due… 
Highly Cited
2005
Highly Cited
2005
The Vitamin D Receptor, Runx2, and the Notch Signaling Pathway Cooperate in the Transcriptional Regulation of Osteopontin*
Osteopontin (OPN), a glycosylated phosphoprotein that binds calcium, is present in bone extracellular matrix and has been… 
Highly Cited
2005
Highly Cited
2005
Meningioma transcript profiles reveal deregulated Notch signaling pathway.
Meningiomas constitute the second most common central nervous system tumor, and yet relatively little is known about the… 
Highly Cited
2004
Highly Cited
2004
Evidence for the notch signaling pathway on the role of estrogen in angiogenesis.
We have investigated the molecular mechanisms involved in 17 beta-estradiol-induced angiogenic pathway. We show here that 17 beta… 
Highly Cited
2002
Highly Cited
2002
The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jkappa (CSL), the target of the Notch signaling pathway.
The RTA protein of the Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is responsible for the switch from latency to lytic… 
Highly Cited
2002
Highly Cited
2002
Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway.
The Notch signaling pathway regulates the commitment and early development of T lymphocytes. We studied Notch-mediated induction… 
Review
2001
Review
2001
Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development.
Highly Cited
2001
Highly Cited
2001
The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway.
We have identified a gene encoding a novel protein that is transcriptionally regulated by the Notch signaling pathway in mammals… 
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