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Noonan Syndrome 4

Known as: NS4 
National Institutes of Health

Related topics

Related topics

15 relations
Acquired cubitus valgusAutosomal dominant inheritanceBlepharoptosisCongenital Heart Defects
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Broader (1)

Noonan Syndrome

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Identification and Characterization of a Novel Non-Structural Protein of Bluetongue Virus
Bluetongue virus (BTV) is the causative agent of a major disease of livestock (bluetongue). For over two decades, it has been… 
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Highly Cited
2011
Highly Cited
2011
Detection of a Fourth Orbivirus Non-Structural Protein
The genus Orbivirus includes both insect and tick-borne viruses. The orbivirus genome, composed of 10 segments of dsRNA, encodes… 
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Highly Cited
1998
Highly Cited
1998
Analysis of Hepatitis C Virus-Inoculated Chimpanzees Reveals Unexpected Clinical Profiles
ABSTRACT The clinical course of hepatitis C virus (HCV) infections in a chimpanzee cohort was examined to better characterize the… 
Highly Cited
1994
Highly Cited
1994
Production of nonstructural proteins of hepatitis C virus requires a putative viral protease encoded by NS3.
Hepatitis C virus (HCV) is a positive strand RNA virus with certain similarity to flaviviruses and pestiviruses. To examine the… 
Highly Cited
1993
Highly Cited
1993
NS3 is a serine protease required for processing of hepatitis C virus polyprotein
Hepatitis C virus (HCV) possesses a positive-sense RNA genome which encodes a large polyprotein of 3,010 amino acids. Previous… 
Highly Cited
1993
Highly Cited
1993
Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions
We have studied processing of the nonstructural (NS) polyprotein of the hepatitis C virus. A series of cDNAs corresponding to… 
Highly Cited
1993
Highly Cited
1993
T-lymphocyte response to hepatitis C virus in different clinical courses of infection.
Highly Cited
1993
Highly Cited
1993
Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C
The adult liver is an organ without constitutive lymphoid components. Therefore, any intrahepatic T cell found in chronic… 
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Highly Cited
1993
Highly Cited
1993
Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site
Flavivirus proteins are produced by co- and posttranslational proteolytic processing of a large polyprotein by both host- and… 
Highly Cited
1992
Highly Cited
1992
Genetic drift of hepatitis C virus during an 8.2-year infection in a chimpanzee: variability and stability.
Extensive variability in genomic sequence, especially at "hypervariable regions" within the NS1/E2 region of the long open… 
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