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Noonan Syndrome 4

Known as: NS4 
 
National Institutes of Health

Related topics

Related topics

15 relations
Acquired cubitus valgusAutosomal dominant inheritanceBlepharoptosisCongenital Heart Defects
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Broader (1)

Noonan Syndrome

Papers overview

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Highly Cited
2011
Highly Cited
2011
Identification and Characterization of a Novel Non-Structural Protein of Bluetongue Virus
Bluetongue virus (BTV) is the causative agent of a major disease of livestock (bluetongue). For over two decades, it has been… Expand
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Highly Cited
2011
Highly Cited
2011
Detection of a Fourth Orbivirus Non-Structural Protein
The genus Orbivirus includes both insect and tick-borne viruses. The orbivirus genome, composed of 10 segments of dsRNA, encodes… Expand
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Highly Cited
1998
Highly Cited
1998
Analysis of Hepatitis C Virus-Inoculated Chimpanzees Reveals Unexpected Clinical Profiles
ABSTRACT The clinical course of hepatitis C virus (HCV) infections in a chimpanzee cohort was examined to better characterize the… Expand
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Highly Cited
1994
Highly Cited
1994
Different genotypes of hepatitis C virus are associated with different severity of chronic liver disease
The presence of the “Japanese type” NS4 region was investigated in two series of patients (53 from Italy and 58 from Japan) with… Expand
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Highly Cited
1993
Highly Cited
1993
NS3 is a serine protease required for processing of hepatitis C virus polyprotein.
Hepatitis C virus (HCV) possesses a positive-sense RNA genome which encodes a large polyprotein of 3,010 amino acids. Previous… Expand
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Highly Cited
1993
Highly Cited
1993
Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions.
We have studied processing of the nonstructural (NS) polyprotein of the hepatitis C virus. A series of cDNAs corresponding to… Expand
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Highly Cited
1993
Highly Cited
1993
T-lymphocyte response to hepatitis C virus in different clinical courses of infection.
BACKGROUND To assess the role played by the immune response in the outcome of hepatitis C virus infection, the CD4+ T-lymphocyte… Expand
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Highly Cited
1993
Highly Cited
1993
Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C
The adult liver is an organ without constitutive lymphoid components. Therefore, any intrahepatic T cell found in chronic… Expand
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Highly Cited
1993
Highly Cited
1993
Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site.
Flavivirus proteins are produced by co- and posttranslational proteolytic processing of a large polyprotein by both host- and… Expand
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Highly Cited
1992
Highly Cited
1992
Genetic drift of hepatitis C virus during an 8.2-year infection in a chimpanzee: variability and stability.
Extensive variability in genomic sequence, especially at "hypervariable regions" within the NS1/E2 region of the long open… Expand
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