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Nitrendipine

Known as: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester, 1,4-dihydro-2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester, Nitrendipinum 
A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers… Expand
National Institutes of Health

Related topics

Related topics

26 relations

Broader (5)

Antihypertensive AgentsCalcium Channel BlockersVasodilator Agentsdihydropyridine
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BayotensinIn Bloodagonistsanalogs & derivatives
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Narrower (13)

BaypresolBaypressMRS 1845Nidrel
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Preparation of stable nitrendipine nanosuspensions using the precipitation-ultrasonication method for enhancement of dissolution and oral bioavailability.
The aim of this study was to prepare and characterize nitrendipine nanosuspensions to enhance the dissolution rate and oral… Expand
Highly Cited
2005
Highly Cited
2005
Morbidity and Mortality After Stroke, Eprosartan Compared With Nitrendipine for Secondary Prevention: Principal Results of a Prospective Randomized Controlled Study (MOSES)
Background and Purpose— In hypertensive stroke patients, for the same level of blood pressure control, eprosartan will be more… Expand
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Highly Cited
1999
Highly Cited
1999
Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension.
ContextThe clinical use of ambulatory blood pressure (BP) monitoring requires further validation in prospective outcome studies… Expand
Highly Cited
1999
Highly Cited
1999
Effects of Calcium-Channel Blockade in Older Patients with Diabetes and Systolic Hypertension
Background Recent reports suggest that calcium-channel blockers may be harmful in patients with diabetes and hypertension. We… Expand
Highly Cited
1998
Highly Cited
1998
Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial
BACKGROUND Systolic hypertension increases the risk of dementia in elderly people. The vascular dementia project, set up in the… Expand
Highly Cited
1988
Highly Cited
1988
Dominant role of N-type Ca2+ channels in evoked release of norepinephrine from sympathetic neurons.
Multiple types of calcium channels have been found in neurons, but uncertainty remains about which ones are involved in stimulus… Expand
Highly Cited
1984
Highly Cited
1984
Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.
  • B. Bean
  • Proceedings of the National Academy of Sciences…
  • 1984
    • Corpus ID: 10764834
Block of Ca2+ currents by the dihydropyridine drug nitrendipine was studied in single canine ventricular cells by using the whole… Expand
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Highly Cited
1984
Highly Cited
1984
Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists
Single cardiac transmembranous Ca channels have three modes of gating behaviour in the absence of drugs, expressed as current… Expand
Highly Cited
1983
Highly Cited
1983
Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells
Organic inhibitors of calcium influx prevent outward as well as inward current through cardiac calcium channels but do not slow… Expand
Highly Cited
1983
Highly Cited
1983
[3H]nitrendipine receptors in skeletal muscle.
The richest source of receptors for the organic calcium channel blocker [3H]nitrendipine in muscle is the transverse tubule… Expand
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