Nitrendipine

Known as: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester, 1,4-dihydro-2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester, Nitrendipinum 
A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers… (More)
National Institutes of Health

Related topics

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23 relations

Broader (5)

Antihypertensive AgentsCalcium Channel BlockersVasodilator Agentsdihydropyridine
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BayotensinIn Bloodagonistsanalogs & derivatives
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Narrower (10)

BaypresolBaypressMRS 1845Nidrel
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Papers overview

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Highly Cited
1999
Highly Cited
1999
Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension. Systolic Hypertension in Europe Trial Investigators.
CONTEXT The clinical use of ambulatory blood pressure (BP) monitoring requires further validation in prospective outcome studies… (More)
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Highly Cited
1998
Highly Cited
1998
Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial
BACKGROUND Systolic hypertension increases the risk of dementia in elderly people. The vascular dementia project, set up in the… (More)
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Highly Cited
1997
Highly Cited
1997
Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators.
BACKGROUND Isolated systolic hypertension occurs in about 15% of people aged 60 years or older. In 1989, the European Working… (More)
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Highly Cited
1989
Highly Cited
1989
Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current.
Early afterdepolarizations (EADs) are a type of triggered activity found in heart muscle. We used voltage-clamped sheep cardiac… (More)
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Highly Cited
1988
Highly Cited
1988
Dominant role of N-type Ca2+ channels in evoked release of norepinephrine from sympathetic neurons.
Multiple types of calcium channels have been found in neurons, but uncertainty remains about which ones are involved in stimulus… (More)
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Highly Cited
1985
Highly Cited
1985
Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology
Currents through Ca channels were recorded in single canine atrial cells using whole-cell recording with patch pipettes. Two… (More)
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Highly Cited
1984
Highly Cited
1984
Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.
Block of Ca2+ currents by the dihydropyridine drug nitrendipine was studied in single canine ventricular cells by using the whole… (More)
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Highly Cited
1984
Highly Cited
1984
Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists
Single cardiac transmembranous Ca channels have three modes of gating behaviour in the absence of drugs, expressed as current… (More)
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Highly Cited
1983
Highly Cited
1983
Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells
Organic inhibitors of calcium influx prevent outward as well as inward current through cardiac calcium channels but do not slow… (More)
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Highly Cited
1983
Highly Cited
1983
[3H]nitrendipine receptors in skeletal muscle.
The richest source of receptors for the organic calcium channel blocker [3H]nitrendipine in muscle is the transverse tubule… (More)
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