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Nitrendipine

Known as: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester, 1,4-dihydro-2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester, Nitrendipinum 
A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers… 
National Institutes of Health

Related topics

Related topics

26 relations

Broader (5)

Antihypertensive AgentsCalcium Channel BlockersVasodilator Agentsdihydropyridine
BayotensinIn Bloodagonistsanalogs & derivatives

Narrower (13)

BaypresolBaypressMRS 1845Nidrel

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1993
Highly Cited
1993
Effects of nitrendipine on glucose tolerance and serum insulin and dehydroepiandrosterone sulfate levels in insulin-resistant obese and hypertensive men.
To determine whether the calcium channel blocker nitrendipine improves glucose tolerance, lowers circulating insulin, and raises… 
1990
1990
Effects of Nitrendipine and Cilazapril on Renal Hemodynamics and Albuminuria in Hypertensive Patients with Chronic Renal Failure
Summary: In 11 hypertensive patients with chronic renal failure we studied the short-term effects of the calcium antagonist… 
1987
1987
Pharmacokinetics of Nitrendipine in Elderly and Young Healthy Volunteers
This study was designed to compare the pharmacokinetics of nitrendipine in young and old healthy volunteers. Single 20 mg oral… 
1987
1987
Nitrendipine as an Antagonist to the Cardiac Toxicity of Cocaine
Cocaine (10−7–10−4) administered to the isolated heart increases rate in the presence of a stable or decreased coronary flow… 
1986
1986
Identification of two calcium channel receptor sites for [3H]nitrendipine in mammalian cardiac and smooth muscle membrane.
Various Ca-channel blockers differ in cardiovascular action despite common effects at the Ca channel. Many investigators have… 
Highly Cited
1985
Highly Cited
1985
Calcium channel antagonists inhibit the acrosome reaction and bind to plasma membranes of sea urchin sperm.
As a prerequisite to fertilization, sea urchin sperm undergo an acrosome reaction that is mediated in part by increased… 
1983
1983
Nitrendipine and other calcium entry blockers (calcium antagonists) in hypertension.
Nitrendipine is a calcium antagonistic 1,4-dihydropyridine derivative with a pronounced antihypertensive activity in animal… 
1983
1983
Effect of nitrendipine on coronary flow and ventricular hypertrophy in hypertension.
Calcium entry blockers have direct myocardial and vascular effects that can influence the way the heart responds to their use as… 
1983
1983
Pharmacokinetic and pharmacodynamic parameters in patients treated with nitrendipine.
Nitrendipine (BAY e 5009) is a new calcium channel blocker with a marked effect on excitation-contraction coupling in different… 
Highly Cited
1982
Highly Cited
1982
Binding of a calcium antagonist, [3H]nitrendipine, to high affinity sites in bovine aortic smooth muscle and canine cardiac membranes.
[(3)H]Nitrendipine, a potent calcium channel antagonist [3-ethyl-5-methyl-1-1,4-dihydro-2,6 - dimethyl - 4 - (3 - nitrophenyl…