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Nitrendipine
Known as:
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester
, 1,4-dihydro-2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester
, Nitrendipinum
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A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers…
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National Institutes of Health
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Related topics
Related topics
26 relations
Broader (5)
Antihypertensive Agents
Calcium Channel Blockers
Vasodilator Agents
dihydropyridine
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Bayotensin
In Blood
agonists
analogs & derivatives
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Narrower (13)
Baypresol
Baypress
MRS 1845
Nidrel
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Morbidity and Mortality After Stroke, Eprosartan Compared With Nitrendipine for Secondary Prevention: Principal Results of a Prospective Randomized Controlled Study (MOSES)
J. Schrader
,
S. Lüders
,
+6 authors
H. Diener
Stroke
2005
Corpus ID: 2514199
Background and Purpose— In hypertensive stroke patients, for the same level of blood pressure control, eprosartan will be more…
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Highly Cited
2002
Highly Cited
2002
The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study.
F. Forette
,
M. Seux
,
+14 authors
W. Birkenhäger
Archives of Internal Medicine
2002
Corpus ID: 21669307
BACKGROUND After the double-blind, placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial ended in February 1997…
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Highly Cited
1999
Highly Cited
1999
Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension.
J. Staessen
,
L. Thijs
,
+9 authors
J. Webster
1999
Corpus ID: 72970904
ContextThe clinical use of ambulatory blood pressure (BP) monitoring requires further validation in prospective outcome studies…
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Highly Cited
1998
Highly Cited
1998
Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial
F. Forette
,
M. Seux
,
+15 authors
R. Fagard
The Lancet
1998
Corpus ID: 20693800
Highly Cited
1991
Highly Cited
1991
Ca2+ channels in rat central and peripheral neurons: High-threshold current resistant to dihydropyridine blockers and ω-conotoxin
L. J. Regan
,
D. Sah
,
B. Bean
Neuron
1991
Corpus ID: 21821044
Highly Cited
1991
Highly Cited
1991
Study of the mechanisms of hydrogen peroxide and hydroxyl free radical-induced cellular injury and calcium overload in cardiac myocytes.
R. Josephson
,
H. Silverman
,
E. Lakatta
,
M. Stern
,
J. Zweier
Journal of Biological Chemistry
1991
Corpus ID: 35718187
Highly Cited
1988
Highly Cited
1988
Dominant role of N-type Ca2+ channels in evoked release of norepinephrine from sympathetic neurons.
L. D. Hirning
,
A. Fox
,
+4 authors
R. Tsien
Science
1988
Corpus ID: 29966263
Multiple types of calcium channels have been found in neurons, but uncertainty remains about which ones are involved in stimulus…
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Highly Cited
1984
Highly Cited
1984
Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.
B. Bean
Proceedings of the National Academy of Sciences…
1984
Corpus ID: 10764834
Block of Ca2+ currents by the dihydropyridine drug nitrendipine was studied in single canine ventricular cells by using the whole…
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Highly Cited
1984
Highly Cited
1984
Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists
P. Hess
,
J. Lansman
,
R. Tsien
Nature
1984
Corpus ID: 4236555
Single cardiac transmembranous Ca channels have three modes of gating behaviour in the absence of drugs, expressed as current…
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Highly Cited
1983
Highly Cited
1983
Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells
K. S. Lee
,
R. Tsien
Nature
1983
Corpus ID: 4320543
Organic inhibitors of calcium influx prevent outward as well as inward current through cardiac calcium channels but do not slow…
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