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Nitrendipine
Known as:
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester
, 1,4-dihydro-2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester
, Nitrendipinum
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A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers…
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National Institutes of Health
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Related topics
Related topics
26 relations
Broader (5)
Antihypertensive Agents
Calcium Channel Blockers
Vasodilator Agents
dihydropyridine
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Bayotensin
In Blood
agonists
analogs & derivatives
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Narrower (13)
Baypresol
Baypress
MRS 1845
Nidrel
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Preparation of stable nitrendipine nanosuspensions using the precipitation-ultrasonication method for enhancement of dissolution and oral bioavailability.
Dengning Xia
,
P. Quan
,
+4 authors
F. Cui
European journal of pharmaceutical sciences…
2010
Corpus ID: 440265
The aim of this study was to prepare and characterize nitrendipine nanosuspensions to enhance the dissolution rate and oral…
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Highly Cited
2005
Highly Cited
2005
Morbidity and Mortality After Stroke, Eprosartan Compared With Nitrendipine for Secondary Prevention: Principal Results of a Prospective Randomized Controlled Study (MOSES)
J. Schrader
,
S. Lueders
,
+6 authors
H. C. Diener
Stroke
2005
Corpus ID: 2514199
Background and Purpose— In hypertensive stroke patients, for the same level of blood pressure control, eprosartan will be more…
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Highly Cited
1999
Highly Cited
1999
Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension.
J. Staessen
,
L. Thijs
,
+9 authors
J. Webster
1999
Corpus ID: 72970904
ContextThe clinical use of ambulatory blood pressure (BP) monitoring requires further validation in prospective outcome studies…
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Highly Cited
1999
Highly Cited
1999
Effects of Calcium-Channel Blockade in Older Patients with Diabetes and Systolic Hypertension
J. Tuomilehto
,
D. Rastenytė
,
+9 authors
R. Fagard
1999
Corpus ID: 71225998
Background Recent reports suggest that calcium-channel blockers may be harmful in patients with diabetes and hypertension. We…
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Highly Cited
1998
Highly Cited
1998
Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial
on behalf of the Syst-Eur Investigators
,
F. Forette
,
Marie-Laure Seux
,
J. Staessen
,
R. Fagard
The Lancet
1998
Corpus ID: 20693800
BACKGROUND Systolic hypertension increases the risk of dementia in elderly people. The vascular dementia project, set up in the…
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Highly Cited
1988
Highly Cited
1988
Dominant role of N-type Ca2+ channels in evoked release of norepinephrine from sympathetic neurons.
L. D. Hirning
,
A. Fox
,
+4 authors
R. Tsien
Science
1988
Corpus ID: 29966263
Multiple types of calcium channels have been found in neurons, but uncertainty remains about which ones are involved in stimulus…
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Highly Cited
1984
Highly Cited
1984
Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.
B. Bean
Proceedings of the National Academy of Sciences…
1984
Corpus ID: 10764834
Block of Ca2+ currents by the dihydropyridine drug nitrendipine was studied in single canine ventricular cells by using the whole…
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Highly Cited
1984
Highly Cited
1984
Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists
P. Hess
,
J. Lansman
,
R. Tsien
Nature
1984
Corpus ID: 4236555
Single cardiac transmembranous Ca channels have three modes of gating behaviour in the absence of drugs, expressed as current…
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Highly Cited
1983
Highly Cited
1983
Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells
K. Lee
,
R. Tsien
Nature
1983
Corpus ID: 4320543
Organic inhibitors of calcium influx prevent outward as well as inward current through cardiac calcium channels but do not slow…
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Highly Cited
1983
Highly Cited
1983
[3H]nitrendipine receptors in skeletal muscle.
M. Fosset
,
E. Jaimovich
,
E. Delpont
,
M. Lazdunski
The Journal of biological chemistry
1983
Corpus ID: 41189051
The richest source of receptors for the organic calcium channel blocker [3H]nitrendipine in muscle is the transverse tubule…
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