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Nigericin

Known as: Nigericin [Chemical/Ingredient] 
A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck… 
National Institutes of Health

Related topics

Related topics

22 relations

Narrower (12)

2-epimutalomycin28-epimutalomycinA-130BA-130C

Broader (2)

Anti-Bacterial AgentsIonophores
EpinigericinIn Bloodagonistsanalogs & derivatives

Papers overview

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2005
2005
Relationship between membrane permeability and the translation capacity of human HeLa cells studied by means of the ionophore nigericin.
Treatment of HeLa cells with the ionophore nigericin causes a drastic inhibition of protein synthesis which is dependent on the… 
Highly Cited
1989
Highly Cited
1989
Hydrogen ion-mediated enhancement of cytotoxicity of bis-chloroethylating drugs in rat mammary carcinoma cells in vitro.
Aerobic glycolysis, a metabolic characteristic of malignant cells, can be exploited to increase the concentration of lactic acid… 
Highly Cited
1985
Highly Cited
1985
Evidence for a role for cellular alkalinization in the cyclic adenosine 3',5'-monophosphate-mediated initiation of motility in bovine caput spermatozoa.
Bicarbonate ion, the local anesthetics procaine and dibucaine, and the ionophores monensin and nigericin have been shown to… 
1983
1983
Effect of N, N'-dicyclohexylcarbodiimide and nigericin on Staphylococcus aureus susceptibility to gentamicin
The abilities of the H+-ATPase inhibitor N, N'-dicyclohexylcarbodiimide and the antibiotic ionophore nigericin to enhance the… 
Highly Cited
1982
Highly Cited
1982
Bioenergetics of serotonin transport by membrane vesicles derived from platelet dense granules.
A population of membrane vesicles derived from platelet-dense granules was isolated from platelet osmotic lysates by density… 
1978
1978
Thallium-205 and proton nuclear magnetic resonance investigation of the complexation of thallium by the ionophores monensin and nigericin.
A thallium-205 and proton nuclear magnetic resonance study of the ionophores monensin and nigericin is reported. Evidence is… 
1978
1978
Hydroxytryptamine transport by the bovine chromaffin-granule membrane.
5-Hydroxytryptamine is accumulated by resealed chromaffin-granule 'ghosts' if a pH gradient (acid inside) is imposed across their… 
Highly Cited
1974
Highly Cited
1974
Analysis of the reactivity of SH-reagents with the mitochondrial phosphate carrier.
The inhibition of mitochondrial Pi transport by SH-reagents was investigated together with incorporation of SH-reagents into… 
1971
1971
Microcalorimetric determination of H 0 , G 0 and S 0 for the interaction of the carrier antibiotics nigericin and monensin with sodium and potassium ions.
The thermodynamic parameters ΔH0, ΔG0 and ΔS0 – and thereby the equilibrium constants – for the complexation of the carrier… 
Highly Cited
1969
Highly Cited
1969
Correlation between anion uptake and the movement of K+ and H+ across the mitochondrial membrane.
The relationship between the H+ and K+ movement across the mitochondrial membrane and the distribution of anions between the…