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In the last decade, substantial efforts have been made to identify NAD+ biosynthesis inhibitors, specifically against… Expand Nicotinamide phosphoribosyltransferase (NAMPT) is a pleiotropic protein with intra- and extra-cellular functions as an enzyme… Expand Olesen UH, Hastrup N, Sehested M. Expression patterns of nicotinamide phosphoribosyltransferase and nicotinic acid… Expand ABSTRACT GMX1777 is a prodrug of the small molecule GMX1778, currently in phase I clinical trials for the treatment of cancer. We… Expand NAD plays critical roles in various biological processes through the function of SIRT1. Although classical studies in mammals… Expand Nicotinamide adenine dinucleotide (NAD) is an essential cofactor for cellular redox reactions and can act as an important… Expand In order to elucidate the NAD-recycling pathway the following enzyme activities have been characterized in different tobacco… Expand Nicotinic acid phosphoribosyltransferase (NAPRTase; EC 22.214.171.124) is a facultative ATPase that uses the energy of ATP hydrolysis… Expand Nicotinic acid phosphoribosyltransferase (NAPRTase; EC 126.96.36.199) forms nicotinic acid mononucleotide (NAMN) and PPi from 5… Expand The ricinine content of etiolated seedlings of Ricinus communis increased nearly 12-fold over a 4-day period. In plants… Expand