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Nicotinamide adenine dinucleotide (NAD)

Known as: DPN, Nicotinamide-Adenine Dinucleotide, Dinucleotide, Dihydronicotinamide Adenine 
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Biological functions of sirtuins may involve lysine desuccinylase and demalonylase activities. Silent information regulator 2… Expand
Review
2009
Review
2009
  • M. Murphy
  • The Biochemical journal
  • 2009
  • Corpus ID: 7977231
The production of ROS (reactive oxygen species) by mammalian mitochondria is important because it underlies oxidative damage in… Expand
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Highly Cited
2009
Highly Cited
2009
Circadian Oscillations The 24-hour day-night cycle plays an important role in mammalian physiology and behavior and, as most… Expand
Highly Cited
2009
Highly Cited
2009
Circadian Oscillations The 24-hour day-night cycle plays an important role in mammalian physiology and behavior and, as most… Expand
Review
2007
Review
2007
Nicotinamide adenine dinucleotide (NAD(+)) is both a coenzyme for hydride-transfer enzymes and a substrate for NAD(+)-consuming… Expand
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Highly Cited
2004
Highly Cited
2004
Axonal degeneration is an active program of self-destruction that is observed in many physiological and pathological settings. In… Expand
Highly Cited
2001
Highly Cited
2001
Clock:BMAL1 and NPAS2:BMAL1 are heterodimeric transcription factors that control gene expression as a function of the light-dark… Expand
Highly Cited
2000
Highly Cited
2000
Yeast Sir2 is a heterochromatin component that silences transcription at silent mating loci, telomeres and the ribosomal DNA, and… Expand
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Highly Cited
2000
Highly Cited
2000
Calorie restriction extends life-span in a wide variety of organisms. Although it has been suggested that calorie restriction may… Expand
Highly Cited
1967
Highly Cited
1967
1. The concentrations of the oxidized and reduced substrates of the lactate-, beta-hydroxybutyrate- and glutamate-dehydrogenase… Expand
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