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Nicotinamide adenine dinucleotide (NAD)

Known as: DPN, Nicotinamide-Adenine Dinucleotide, Dinucleotide, Dihydronicotinamide Adenine 
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Poly (ADP-ribose) polymerases (PARPs) play an important role in various cellular processes, such as replication, recombination… Expand
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Review
2019
Review
2019
The rising incidence of type 2 diabetes mellitus (T2DM) is a major public health concern, and novel therapeutic strategies to… Expand
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Review
2019
Review
2019
ATP, NAD+, and nucleic acids are abundant purines that, in addition to having critical intracellular functions, have evolved… Expand
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Review
2018
Review
2018
In this review, the potential causes of ageing are discussed. We seek to gain insight into the main physiological functions of… Expand
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Highly Cited
2009
Highly Cited
2009
Circadian Oscillations The 24-hour day-night cycle plays an important role in mammalian physiology and behavior and, as most… Expand
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Highly Cited
2004
Highly Cited
2004
Axonal degeneration is an active program of self-destruction that is observed in many physiological and pathological settings. In… Expand
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Highly Cited
2001
Highly Cited
2001
Clock:BMAL1 and NPAS2:BMAL1 are heterodimeric transcription factors that control gene expression as a function of the light-dark… Expand
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Highly Cited
2000
Highly Cited
2000
Yeast Sir2 is a heterochromatin component that silences transcription at silent mating loci, telomeres and the ribosomal DNA, and… Expand
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Highly Cited
2000
Highly Cited
2000
Calorie restriction extends life-span in a wide variety of organisms. Although it has been suggested that calorie restriction may… Expand
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Highly Cited
1967
Highly Cited
1967
1. The concentrations of the oxidized and reduced substrates of the lactate-, beta-hydroxybutyrate- and glutamate-dehydrogenase… Expand
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