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Nicorandil

Known as: 2 Nicotinamidethyl Nitrate, 2 Nicotinamidoethyl Nitrate, 2-Nicotinamidethyl Nitrate 
A derivative of the NIACINAMIDE that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of… 
National Institutes of Health

Related topics

Related topics

16 relations

Narrower (4)

AdancorDancorIkorelSG-75

Broader (5)

Anti-Arrhythmia AgentsAntihypertensive AgentsNiacinamideVasodilator Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Nicorandil and Idiopathic Anal Ulceration
PURPOSESeveral reports have implicated nicorandil as a reversible cause of anal ulceration. We have recently commenced a… 
Highly Cited
2004
Highly Cited
2004
Synergistic effect of Nicorandil and Amlodipine on tissue defense system during experimental myocardial infarction in rats
The synergistic protective effect of Nicorandil (KATP channel opener) and Amlodipine (calcium channel blocker) on heart tissue… 
Highly Cited
2003
Highly Cited
2003
Intravenous nicorandil in conjunction with coronary reperfusion therapy is associated with better clinical and functional outcomes in patients with acute myocardial infarction.
The aim of this retrospective study was to assess whether intravenous nicorandil, a hybrid of NO and a KATP channel opener, in… 
2002
2002
Nicorandil and Leukocyte Activation
Nicorandil, a hybrid compound of an ATP-sensitive potassium (KATP) channel opener and a nitric oxide donor, has been reported to… 
Highly Cited
2001
Highly Cited
2001
Structural basis for the interference between nicorandil and sulfonylurea action.
Nicorandil is a new antianginal agent that potentially may be used to treat the cardiovascular side effects of diabetes. It is… 
1993
1993
Effects of nitric oxide-containing compounds on increases in cytosolic ionized Ca2+ and on aggregation of human platelets.
Highly Cited
1993
Highly Cited
1993
Pharmacological properties of ATP-sensitive K+ channels in mammalian skeletal muscle cells.
1990
1990
Prostaglandin redirection by thromboxane synthetase inhibition. Attenuation of myocardial stunning in canine heart.
We have previously reported that inhibition of thromboxane synthesis results in an improvement in postischemic function in… 
Highly Cited
1989
Highly Cited
1989
Functional changes in potassium channels in aortas from rats with streptozotocin-induced diabetes.
1988
1988
Cromakalim, a Potassium Channel Activator: A Comparison of its Cardiovascular Haemodynamic Profile and Tissue Specificity with those of Pinacidil and Nicorandil
Studies have been performed to compare the cardiovascular haemodynamic profiles of the potassium channel activator, cromakalim… 
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