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Nicardipine

Known as: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-(methyl(phenylmethyl)amino)ethyl ester, Nicardipinum, Nicardipino 
A synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain… 
National Institutes of Health

Related topics

Related topics

38 relations
10 ML Nicardipine hydrochloride 2.5 MG/ML Injection12 HR Nicardipine hydrochloride 60 MG Extended Release Oral Capsule [Cardene]Angina Pectoris, VariantAortic Valve Stenosis

Narrower (13)

12 HR Nicardipine hydrochloride 45 MG Extended Release Oral Capsule200 ML Nicardipine hydrochloride 0.2 MG/ML InjectionCardeneCardene I.V.

Broader (4)

Antihypertensive AgentsCalcium Channel BlockersVasodilator Agentspyridine carboxylate

Papers overview

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Highly Cited
2008
Highly Cited
2008
The ECLIPSE Trials: Comparative Studies of Clevidipine to Nitroglycerin, Sodium Nitroprusside, and Nicardipine for Acute Hypertension Treatment in Cardiac Surgery Patients
BACKGROUND: Acute hypertension during cardiac surgery can be difficult to manage and may adversely affect patient outcomes… 
Review
2007
Review
2007
Hypertensive crises: challenges and management.
Hypertension affects > 65 million people in the United States and is one of the leading causes of death. One to two percent of… 
Highly Cited
2004
Highly Cited
2004
Preliminary experience with intra-arterial nicardipine as a treatment for cerebral vasospasm.
BACKGROUND AND PURPOSE Papaverine is the primary intra-arterial (IA) treatment for vasospasm after aneurysmal subarachnoid… 
Review
2003
Review
2003
Tacrolimus: a further update of its use in the management of organ transplantation.
UNLABELLED Extensive clinical use has confirmed that tacrolimus (Prograf) is a key option for immunosuppression after… 
Highly Cited
1995
Highly Cited
1995
Medical complications of aneurysmal subarachnoid hemorrhage: a report of the multicenter, cooperative aneurysm study. Participants of the Multicenter Cooperative Aneurysm Study.
OBJECTIVES This report examines the frequency, type, and prognostic factors of medical (nonneurologic) complications after… 
Highly Cited
1993
Highly Cited
1993
Different types of calcium channels mediate central synaptic transmission
SYNAPTIC transmission is mediated by calcium entry through voltage-dependent calcium channels in presynaptic nerve terminals1,2… 
Review
1993
Review
1993
A randomized controlled trial of high-dose intravenous nicardipine in aneurysmal subarachnoid hemorrhage. A report of the Cooperative Aneurysm Study.
Because of their action as cerebral vasodilators, dihydropyridine calcium antagonists have received intense scrutiny for their… 
Review
1989
Review
1989
Verapamil. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension.
Although verapamil is a well-established treatment for angina, cardiac arrhythmias and cardiomyopathies, this review reflects… 
Highly Cited
1988
Highly Cited
1988
Endothelin is a potent secretagogue for atrial natriuretic peptide in cultured rat atrial myocytes.
Highly Cited
1984
Highly Cited
1984
Voltage‐Dependent Block of Calcium Channel Current in the Calf Cardiac Purkinje Fiber by Dihydropyridine Calcium Channel Antagonists
We have investigated the mechanisms of blockade of calcium channel current by the dihydropyridines, e.g. nisoldipine… 
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