Nicardipine

Known as: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-(methyl(phenylmethyl)amino)ethyl ester, Nicardipinum, Nicardipino 
A synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain… (More)
National Institutes of Health

Related topics

Related topics

37 relations
10 ML Nicardipine hydrochloride 2.5 MG/ML Injection12 HR Nicardipine hydrochloride 60 MG Extended Release Oral Capsule [Cardene]Angina Pectoris, VariantAortic Valve Stenosis
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Narrower (12)

12 HR Nicardipine hydrochloride 45 MG Extended Release Oral Capsule200 ML Nicardipine hydrochloride 0.2 MG/ML InjectionCardeneCardene I.V.
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Broader (4)

Antihypertensive AgentsCalcium Channel BlockersVasodilator Agentspyridine carboxylate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Intravenous Nicardipine
Nicardipine is a water soluble calcium channel antagonist, with predominantly vasodilatory actions. Intravenous (IV) nicardipine… (More)
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Highly Cited
2004
Highly Cited
2004
Preliminary experience with intra-arterial nicardipine as a treatment for cerebral vasospasm.
BACKGROUND AND PURPOSE Papaverine is the primary intra-arterial (IA) treatment for vasospasm after aneurysmal subarachnoid… (More)
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Highly Cited
2003
Highly Cited
2003
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
Some small molecules, often hits from screening, form aggregates in solution that inhibit many enzymes. In contrast, drugs are… (More)
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Highly Cited
1997
Highly Cited
1997
D 1 Receptor Activation Enhances Evoked Discharge in Neostriatal Medium Spiny Neurons by Modulating an L-Type Ca 2 1 Conductance
Most in vitro studies of D1 dopaminergic modulation of excitability in neostriatal medium spiny neurons have revealed inhibitory… (More)
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Highly Cited
1995
Highly Cited
1995
Medical complications of aneurysmal subarachnoid hemorrhage: a report of the multicenter, cooperative aneurysm study. Participants of the Multicenter Cooperative Aneurysm Study.
OBJECTIVES This report examines the frequency, type, and prognostic factors of medical (nonneurologic) complications after… (More)
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Highly Cited
1993
Highly Cited
1993
Different types of calcium channels mediate central synaptic transmission
SYNAPTIC transmission is mediated by calcium entry through voltage-dependent calcium channels in presynaptic nerve terminals1,2… (More)
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Highly Cited
1990
Highly Cited
1990
A controlled clinical trial to assess the effect of a calcium channel blocker on the progression of coronary atherosclerosis.
To determine whether calcium channel blockers influence the progression of coronary atherosclerosis, 383 patients age 65 years or… (More)
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Highly Cited
1989
Highly Cited
1989
Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM…
The calcium channel blocker verapamil has been shown to reverse multidrug resistance (T. Tsuruo et al., Cancer Res. 41: 1967-1972… (More)
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1985
1985
Coronary and systemic hemodynamic effects of nicardipine.
Systemic and coronary hemodynamic effects of a new dihydropyridine calcium antagonist, nicardipine, were studied in 15 patients… (More)
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Highly Cited
1983
Highly Cited
1983
Circumvention of vincristine and Adriamycin resistance in vitro and in vivo by calcium influx blockers.
Calcium influx blockers, diltiazem, nicardipine, nifedipine, niludipine, and nimodipine, which possess coronary vasodilator… (More)
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