Neutrophil Cytosolic Factor 2

Known as: 67 kDa Neutrophil Oxidase Factor, Neutrophil Cytosolic Factor 2 (65kD, Chronic Granulomatous Disease, Autosomal 2), Neutrophil NADPH Oxidase Factor 2 
Neutrophil cytosol factor 2 (526 aa, ~60 kDa) is encoded by the human NCF2 gene. This protein plays a role in the generation of superoxide in… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
051019932017

Papers overview

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Highly Cited
2007
Highly Cited
2007
Nonphagocytic NADPH oxidases have recently been suggested to play a major role in the regulation of physiological and… (More)
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Highly Cited
2005
Highly Cited
2005
Amyloid beta peptides generate oxidative stress in hippocampal astrocytes through a mechanism sensitive to inhibitors of the… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Reactive oxygen species (ROS) contribute to the development of heart failure. A potential source of myocardial ROS is… (More)
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Highly Cited
2003
Highly Cited
2003
The catalytic core of a superoxide-producing NADPH oxidase (Nox) in phagocytes is gp91phox/Nox2, a membrane-integrated protein… (More)
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Highly Cited
2003
Highly Cited
2003
Superoxide production by phagocytes involves activation of a multi-component NADPH oxidase. Recently, several homologues of the… (More)
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Highly Cited
2002
Highly Cited
2002
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) may exert direct effects on vascular cells and beneficially… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Adrenomedullin (AM), a potent vasodilator peptide, is produced by posttranslational splicing of pro-adrenomedullin… (More)
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Highly Cited
2001
Highly Cited
2001
The production of reactive oxygen species (ROS) by neutrophils has a vital role in defence against a range of infectious agents… (More)
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Highly Cited
2000
Highly Cited
2000
p67phox is an essential part of the NADPH oxidase, a multiprotein enzyme complex that produces superoxide ions in response to… (More)
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Highly Cited
1994
Highly Cited
1994
Rho and Rac, two members of the Ras superfamily of guanosine triphosphate (GTP)-binding proteins, regulate a variety of signal… (More)
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