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Neurokinin-1 Receptor Antagonists

Known as: Receptor Blockers, Neuroleukin-1, Receptor Antagonists, Neurokinin-1, Neurokinin 1 Receptor Antagonists 
Compounds that inhibit or block the activity of NEUROKININ-1 RECEPTORS.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
The tachykinins, exemplified by substance P, are one of the most intensively studied neuropeptide families. They comprise a… Expand
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Review
2013
Review
2013
Introduction: The substance P (SP)/neurokinin (NK)-1 receptor system is involved in many pathological processes. NK-1 receptor… Expand
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2012
2012
The last decades have seen no significant progress in extending the survival of lung cancer patients and there is an urgent need… Expand
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2007
2007
Background:Neurokinins (e.g., substance P) contribute to pain transmission in the central nervous system, peripheral neurogenic… Expand
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Highly Cited
2003
Highly Cited
2003
Previously, we have shown that primary afferent sensory neurons are necessary for disease activity in T cell-mediated immune… Expand
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Highly Cited
2001
Highly Cited
2001
In this study the localizations of tachykinin neurokinin-1 (NK1) and neurokinin-3 (NK3) receptors in the guinea-pig brain are… Expand
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Highly Cited
2000
Highly Cited
2000
The regioselective dibenzylphosphorylation of 2 followed by catalytic reduction in the presence of N-methyl-D-glucamine afforded… Expand
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Highly Cited
1999
Highly Cited
1999
These experiments examined the role of substance P-selective neurokinin 1 receptors in the restraint-induced activation of the… Expand
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Highly Cited
1998
Highly Cited
1998
Neuropathic pain is poorly managed by conventional analgesic therapy, such as non-steroidal anti-inflammatory drugs and opiates… Expand
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Highly Cited
1992
Highly Cited
1992
Two non-peptide substance P antagonists exhibit opposite rank orders of potency for the human and rat neurokinin-1 receptors. CP… Expand
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