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J. Neurochem. (2011) 117, 1047–1054.
Under normal conditions, the proline-directed serine/threonine residues of neurofilament tail-domain repeats are exclusively… Expand 1 We investigated whether withanolide A (WL‐A), isolated from the Indian herbal drug Ashwagandha (root of Withania somnifera… Expand Brain injury following acute and chronic neurological conditions can involve both neuronal perikaryal and axonal damage, yet… Expand Phosphorylation of the neurofilament-H subunit (NF-H) was investigated in rat embryonic brain neurons in culture. A portion of… Expand Extension of dendrites and axons in neurons may compensate and rescue damaged neuronal networks in the dementia brain. Our aim is… Expand Abstract: To investigate the role of phosphorylation in the turnover and transport of neurofilament (NF) proteins in vivo, we… Expand Neurofilaments (NFs) are composed of triplet proteins, NF-H, NF-M, and NF-L. To understand the dynamics of NFs in vivo, we… Expand SummaryNeurofilaments in axons are highly phosphorylated at multiple sites on the 200 kDa neurofilament (neurofilament-H) and 160… Expand Differentiating neurons initially extend neurites that are the precursors of axons and dendrites. The temporal pattern of neurite… Expand