Neurofibromatosis Type 1 Protein

Known as: Neurofibromin 1, neurofibromatosis type 1 protein/gene, NF1-GAP-Related Protein 
The 250 kD neurofibromin product, encoded by the tumor suppressor NF1 gene, is thought to restrict cell proliferation by functioning as a RAS… (More)
National Institutes of Health

Papers overview

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Review
2015
Review
2015
Neurofibromatosis type 1 (NF1) is a common genetic disorder that predisposes affected individuals to tumours. The NF1 gene… (More)
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Highly Cited
2005
Highly Cited
2005
Neurofibromatosis Type 1 (NF1) is a common neurological disorder caused by mutations in the gene encoding Neurofibromin, a p21Ras… (More)
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Highly Cited
2002
Highly Cited
2002
Neurofibromatosis type I (NF1) is one of the most common single-gene disorders that causes learning deficits in humans. Mice… (More)
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Highly Cited
2002
Highly Cited
2002
Individuals with the neurofibromatosis 1 (NF1) inherited tumor syndrome develop low-grade gliomas (astrocytomas) at an increased… (More)
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Highly Cited
2002
Highly Cited
2002
nagie oko, encoding a MAGUK-family protein, is essential for cellular patterning of the retina Wei, X & Malicki, J Nature Genet… (More)
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Highly Cited
1994
Highly Cited
1994
The neurofibromatosis (NF1) gene shows significant homology to mammalian GAP and is an important regulator of the ras signal… (More)
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Highly Cited
1991
Highly Cited
1991
The gene for neurofibromatosis type 1 (NF1) was recently identified by positional cloning. The complete cDNA encodes a… (More)
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1991
1991
The neurofibromatosis type 1 (NF1) gene responsible for von Recklinghausen neurofibromatosis is related to regulators of ras… (More)
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Highly Cited
1990
Highly Cited
1990
The neurofibromatosis type 1 (NF1) protein contains a region of significant sequence similarity to ras p21 GTPase-activating… (More)
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Highly Cited
1990
Highly Cited
1990
Sequencing of the neurofibromatosis gene (NF1) revealed a striking similarity among NF1, yeast IRA proteins, and mammalian GAP… (More)
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