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NF1 gene

Known as: NEUROFIBROMIN 1, Watson disease, nf 1 Genes 
Tumor suppressor genes located on the long arm of human chromosome 17 in the region 17q11.2. Mutation of these genes is thought to cause… 
National Institutes of Health

Related topics

Related topics

36 relations
Atypical NeurofibromaCardiac NeurofibromaCellular NeurofibromaCervical Malignant Peripheral Nerve Sheath Tumor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
The epidemiology of glioma in adults: a "state of the science" review.
Gliomas are the most common primary intracranial tumor, representing 81% of malignant brain tumors. Although relatively rare… 
Review
2013
Review
2013
The Hippo pathway and human cancer
The Hippo pathway controls organ size in diverse species, whereas pathway deregulation can induce tumours in model organisms and… 
Highly Cited
2005
Highly Cited
2005
The NF1 tumor suppressor critically regulates TSC2 and mTOR.
Loss-of-function mutations in the NF1 tumor suppressor gene underlie the familial cancer syndrome neurofibromatosis type I (NF1… 
Review
2000
Review
2000
NF1 gene and neurofibromatosis 1.
Neurofibromatosis 1 (NF1), also known as von Recklinghausen disease, is an autosomal dominant condition caused by mutations of… 
Review
1997
Review
1997
Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies
Abstract Choosing the best genetic strains of mice for developing a new knockout or transgenic mouse requires extensive knowledge… 
Highly Cited
1994
Highly Cited
1994
Tumour predisposition in mice heterozygous for a targeted mutation in Nf1
Human neurofibromatosis type 1 is a dominant disease caused by the inheritance of a mutant allele of the NF1 gene. In order to… 
Highly Cited
1993
Highly Cited
1993
A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor
Highly Cited
1990
Highly Cited
1990
Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients.
Von Recklinghausen neurofibromatosis (NF1) is a common autosomal dominant disorder characterized by abnormalities in multiple… 
Highly Cited
1990
Highly Cited
1990
The neurofibromatosis type 1 gene encodes a protein related to GAP
Highly Cited
1990
Highly Cited
1990
A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations
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