Neostigmine

Known as: Eustigmine, Eustigmin, Synstigmin 
A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and… (More)
National Institutes of Health

Related topics

Related topics

26 relations
Abnormalities, Drug-InducedAtropine / NeostigmineBromidesHypersensitivity
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Broader (4)

Cholinergic AgentsCholinesterase InhibitorsParasympathomimetic AgentsQuaternary Ammonium Compounds

Narrower (5)

Neostigmine MethylsulfatePolstigmineProstigminSyntostigmine
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Papers overview

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Highly Cited
2010
Highly Cited
2010
Reversal of rocuronium-induced neuromuscular blockade with sugammadex compared with neostigmine during sevoflurane anaesthesia: results of a randomised, controlled trial.
BACKGROUND AND OBJECTIVE Sugammadex, a modified gamma-cyclodextrin, is a selective relaxant-binding agent designed to reverse the… (More)
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Highly Cited
2010
Highly Cited
2010
Sugammadex provides faster reversal of vecuronium-induced neuromuscular blockade compared with neostigmine: a multicenter, randomized, controlled trial.
BACKGROUND Sugammadex, a specifically designed gamma-cyclodextrin, is a selective relaxant binding drug that rapidly reverses… (More)
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Highly Cited
2007
Highly Cited
2007
Sugammadex reversal of rocuronium-induced neuromuscular blockade: a comparison with neostigmine-glycopyrrolate and edrophonium-atropine.
BACKGROUND Sugammadex is a modified [gamma] cyclodextrin compound, which encapsulates rocuronium to provide for a rapid reversal… (More)
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Highly Cited
2003
Highly Cited
2003
Clinical correlates with anti-MuSK antibodies in generalized seronegative myasthenia gravis.
The term seronegative myasthenia gravis (SNMG) refers to the generalized disease without detectable anti-acetylcholine receptor… (More)
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2003
2003
Caudal ropivacaine and neostigmine in pediatric surgery.
BACKGROUND Neostigmine has been added to local anesthetics for different nerve blocks. This study was conducted to evaluate… (More)
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Highly Cited
2000
Highly Cited
2000
Interstitial cells of Cajal mediate cholinergic neurotransmission from enteric motor neurons.
Interstitial cells of Cajal (ICC) are interposed between enteric neurons and smooth muscle cells in gastrointestinal muscles. The… (More)
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Highly Cited
1998
Highly Cited
1998
Neostigmine for the treatment of acute colonic pseudo-obstruction.
BACKGROUND Acute colonic pseudo-obstruction -- that is, massive dilation of the colon without mechanical obstruction -- may… (More)
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Highly Cited
1996
Highly Cited
1996
Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome.
OBJECTIVES We examined the modulatory effects of autonomic nervous system and antiarrhythmic drugs on the ST segment in patients… (More)
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1995
1995
Postoperative analgesia from intrathecal neostigmine in sheep.
Spinal neostigmine produces analgesia in chronically prepared rats, but not in sheep. However, since pain itself activates… (More)
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Highly Cited
1973
Highly Cited
1973
Autoimmune response to acetylcholine receptor.
Injection of rabbits with acetylcholine receptor highly purified from the electric organ of Electrophorus electricus emulsified… (More)
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