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Negative Regulation of S Phase

Known as: S Phase Arrest 
S Phase Arrest consists of interference with, or restraint of, activities that regulate the cellular capacity to transit the cell cycle stage… Expand
National Institutes of Health

Related topics

Related topics

8 relations
Cell NucleusCell ProliferationIntercellular Communication ProcessMitogens
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Papers overview

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Highly Cited
2008
Highly Cited
2008
Silence of ClC‐3 chloride channel inhibits cell proliferation and the cell cycle via G1/S phase arrest in rat basilar arterial smooth muscle cells
Abstract.  Objectives: Previously, we have found that the ClC‐3 chloride channel is involved in endothelin‐1 (ET‐1)‐induced rat… Expand
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Highly Cited
2005
Highly Cited
2005
Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
Resveratrol is one of the most extensively studied cancer chemopreventive agents; however, its mechanisms of action are not… Expand
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Highly Cited
2004
Highly Cited
2004
Enhanced Tumor Cell Radiosensitivity and Abrogation of G2 and S Phase Arrest by the Hsp90 Inhibitor 17-(Dimethylaminoethylamino)-17-demethoxygeldanamycin
Purpose: Because of the potential for affecting multiple signaling pathways, inhibition of Hsp90 may provide a strategy for… Expand
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Highly Cited
2003
Highly Cited
2003
Defective S phase chromatin assembly causes DNA damage, activation of the S phase checkpoint, and S phase arrest.
The S phase checkpoint protects the genome from spontaneous damage during DNA replication, although the cause of damage has been… Expand
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Highly Cited
2002
Highly Cited
2002
Cytoplasmic poly(A) polymerases mediate cellular responses to S phase arrest
The S–M checkpoint delays mitosis until DNA replication is complete; cells defective in this checkpoint lose viability when DNA… Expand
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Highly Cited
2001
Highly Cited
2001
The Mouse Mps1p-like Kinase Regulates Centrosome Duplication
The yeast Mps1p protein kinase acts in centrosome duplication and the spindle assembly checkpoint. We demonstrate here that a… Expand
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Highly Cited
2001
Highly Cited
2001
Chemopreventive agent resveratrol, a natural product derived from grapes, reversibly inhibits progression through S and G2 phases of the cell cycle in U937 cells.
Resveratrol, a natural product derived from grapes, has been shown to prevent carcinogenesis in murine models. We report here… Expand
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Highly Cited
2001
Highly Cited
2001
p21Cip1 and p27Kip1Regulate Cell Cycle Reentry after Hypoxic Stress but Are Not Necessary for Hypoxia-Induced Arrest
ABSTRACT We investigated the role of the cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1 in cell cycle regulation during… Expand
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Highly Cited
1997
Highly Cited
1997
rqh1+, a fission yeast gene related to the Bloom‘s and Werner's syndrome genes, is required for reversible S phase arrest
In eukaryotic cells, S phase can be reversibly arrested by drugs that inhibit DNA synthesis or DNA damage. Here we show that… Expand
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Highly Cited
1997
Highly Cited
1997
Abrogation of a mitotic checkpoint by E2 proteins from oncogenic human papillomaviruses correlates with increased turnover of the p53 tumor suppressor protein
Human papillomavirus (HPV) E2 and E1 proteins are required for the replication of viral genomes in vivo. We have examined the… Expand
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