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Necrostatin-5

Known as: Nec-5 cpd 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
ABSTRACT Streptococcus pneumoniae (the pneumococcus) is capable of invading the heart. Herein we observed that pneumococcal… Expand
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Highly Cited
2015
Highly Cited
2015
Necroptosis is a highly pro-inflammatory mode of cell death regulated by RIP (or RIPK)1 and RIP3 kinases and mediated by the… Expand
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2013
2013
The cardioprotective effects of necroptosis inhibitors necrostatin-1 and necrostatin-5 were studied on the isolated heart model… Expand
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Highly Cited
2011
Highly Cited
2011
Dear Editor, Huntington's disease (HD) is characterized clinically by movement abnormalities (i.e. chorea), psychiatric… Expand
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Highly Cited
2008
Highly Cited
2008
Necroptosis is a cellular mechanism of necrotic cell death induced by apoptotic stimuli in the form of death domain receptor… Expand
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Highly Cited
2007
Highly Cited
2007
Necrostatin-5 (Nec-5) is a novel potent small-molecule inhibitor of necroptosis structurally distinct from previously described… Expand
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