Naltrexone hydrochloride

Known as: (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one Hydrochloride, Naltrexone Hydrochloride [Chemical/Ingredient], Naltrexone.HCl 
The hydrochloride salt of naltrexone, a noroxymorphone derivative with competitive opioid antagonistic activity. Naltrexone and its metabolite 6-beta… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2017
05101519752017

Papers overview

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2012
2012
Although contraindicated, coingestion of alcohol and opioids by patients or drug abusers is a major health concern because of… (More)
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2011
2011
This study aimed at preparing and evaluating Span 60-based niosomes for ocular delivery of naltrexone hydrochloride (NTX… (More)
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2010
2010
Recent reports have demonstrated that topical and systemic application of naltrexone markedly improves the characteristic signs… (More)
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2010
2010
OBJECTIVE To assess the efficacy and safety of morphine sulfate and naltrexone hydrochloride extended release capsules (EMBEDA… (More)
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2009
2009
CONTEXT Oral naltrexone hydrochloride effectively antagonizes heroin, but its utility is limited by patient noncompliance… (More)
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Highly Cited
2008
Highly Cited
2008
CONTEXT Naltrexone hydrochloride treatment for alcohol dependence works for some individuals but not for everyone. Asn40Asp, a… (More)
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2006
2006
BACKGROUND Many smokers remain refractory to current therapies, which only partially address weight gain after smoking cessation… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Naltrexone hydrochloride is the first medication approved in the United States for the treatment of alcohol dependence… (More)
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1995
1995
BACKGROUND It is hypothesized that self-injurious behavior (SIB) and symptoms of autism may be due to overactivity in some opioid… (More)
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1982
1982
Naltrexone methylbromide and naloxone methylbromide, quaternary derivatives of naltrexone and naloxone respectively, are assumed… (More)
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