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Naltrexone hydrochloride

Known as: (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one Hydrochloride, Naltrexone Hydrochloride [Chemical/Ingredient], Naltrexone.HCl 
The hydrochloride salt of naltrexone, a noroxymorphone derivative with competitive opioid antagonistic activity. Naltrexone and its metabolite 6-beta… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Importance To date, extended-release naltrexone hydrochloride has not previously been compared directly with opioid medication… Expand
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Highly Cited
2012
Highly Cited
2012
CONTEXT Sustained-release naltrexone implants may improve outcomes of nonagonist treatment of opioid addiction. OBJECTIVE To… Expand
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Highly Cited
2011
Highly Cited
2011
This study aimed at preparing and evaluating Span 60-based niosomes for ocular delivery of naltrexone hydrochloride (NTX… Expand
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Highly Cited
2009
Highly Cited
2009
CONTEXT Oral naltrexone hydrochloride effectively antagonizes heroin, but its utility is limited by patient noncompliance… Expand
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Highly Cited
2008
Highly Cited
2008
CONTEXT Naltrexone hydrochloride treatment for alcohol dependence works for some individuals but not for everyone. Asn40Asp, a… Expand
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Highly Cited
2001
Highly Cited
2001
Abstract.Rationale: Naltrexone, an opioid antagonist, is currently approved as a treatment for heroin dependence. However… Expand
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Highly Cited
1999
Highly Cited
1999
The efficacy of a voucher-based incentive program for improving adherence to outpatient, thrice weekly naltrexone maintenance was… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Naltrexone hydrochloride is the first medication approved in the United States for the treatment of alcohol dependence… Expand
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1989
1989
The effects of naloxone hydrochloride (Narcan) and naltrexone hydrochloride (Trexan) on the pervasive self-injury of a 12-year… Expand
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Highly Cited
1980
Highly Cited
1980
The effect of naltrexone HC1 (NLTRX) on the reinforcing properties of ethanol (EtOH) was evaluated with intravenous self… Expand
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