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Naltrexone hydrochloride

Known as: (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one Hydrochloride, Naltrexone Hydrochloride [Chemical/Ingredient], Naltrexone.HCl 
The hydrochloride salt of naltrexone, a noroxymorphone derivative with competitive opioid antagonistic activity. Naltrexone and its metabolite 6-beta… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Importance More than 42 000 Americans died of opioid overdoses in 2016, and the fatalities continue to increase. This review… Expand
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Highly Cited
2011
Highly Cited
2011
This study aimed at preparing and evaluating Span 60-based niosomes for ocular delivery of naltrexone hydrochloride (NTX… Expand
Highly Cited
2009
Highly Cited
2009
CONTEXT Oral naltrexone hydrochloride effectively antagonizes heroin, but its utility is limited by patient noncompliance… Expand
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Highly Cited
2008
Highly Cited
2008
CONTEXT Naltrexone hydrochloride treatment for alcohol dependence works for some individuals but not for everyone. Asn40Asp, a… Expand
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Highly Cited
2001
Highly Cited
2001
Abstract.Rationale: Naltrexone, an opioid antagonist, is currently approved as a treatment for heroin dependence. However… Expand
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Highly Cited
1999
Highly Cited
1999
The efficacy of a voucher-based incentive program for improving adherence to outpatient, thrice weekly naltrexone maintenance was… Expand
Highly Cited
1992
Highly Cited
1992
Seventy male alcohol-dependent patients participated in a 12-week, double-blind, placebo-controlled trial of naltrexone… Expand
Highly Cited
1989
Highly Cited
1989
The effects of naloxone hydrochloride (Narcan) and naltrexone hydrochloride (Trexan) on the pervasive self-injury of a 12-year… Expand
Highly Cited
1982
Highly Cited
1982
Naltrexone methylbromide and naloxone methylbromide, quaternary derivatives of naltrexone and naloxone respectively, are assumed… Expand
Highly Cited
1980
Highly Cited
1980
The effect of naltrexone HC1 (NLTRX) on the reinforcing properties of ethanol (EtOH) was evaluated with intravenous self… Expand