Semantic Scholar uses AI to extract papers important to this topic.
Inflammasome activation plays a central role in the development of drug‐induced and obesity‐associated liver disease. However… Expand Nonalcoholic steatohepatitis (NASH) is a serious liver disease associated with obesity. Characterized by metabolic syndrome… Expand Chronic low-grade adipose tissue and liver inflammation is a major cause of systemic insulin resistance and is a key component of… Expand Alcoholic liver disease (ALD) is characterized by steatosis and upregulation of proinflammatory cytokines, including IL-1β. IL-1… Expand Hepatocellular carcinoma (HCC), the major form of primary liver cancer, is one of the most deadly human cancers. The pathogenesis… Expand Whereas in most cases a fatty liver remains free of inflammation, 10%‐20% of patients who have fatty liver develop inflammation… Expand Visceral obesity is intimately associated with metabolic disease and adverse health outcomes. However, a direct association… Expand The NF-κB protein is a key player in inflammation. It now seems that it might also activate signalling pathways, in both cancer… Expand The liver lobule is formed by parenchymal cells, i.e., hepatocytes and nonparenchymal cells. In contrast to hepatocytes that… Expand In vitro and in vivo studies suggest that liver fat-storing cells (FSC) may play an important role in the development of liver… Expand