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NVP ABE171
Known as:
4-(8-benzo(1,2,5)oxadiazol-5-yl-(1,7)naphthyridin-6-yl)benzoic acid
, NVP-ABE171
, NVPABE171
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Naphthyridines
Oxadiazoles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Spleen tyrosine kinase inhibition attenuates airway hyperresponsiveness and pollution-induced enhanced airway response in a chronic mouse model of asthma.
P. Pentón
,
Xiaomin Wang
,
+6 authors
C. Chow
Journal of Allergy and Clinical Immunology
2013
Corpus ID: 2501998
2012
2012
Marked differences in the signaling requirements for expression of CD203c and CD11b versus CD63 expression and histamine release in human basophils.
D. MacGlashan
International Archives of Allergy and Immunology
2012
Corpus ID: 45274901
Many techniques are being used to examine the status of circulating human basophils including the enhanced expression of a…
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2012
2012
Abstract LB-122: A phase I dose escalation study of NVP-BGJ398, a selective pan FGFR inhibitor in genetically preselected advanced solid tumors
Jurgen Wolf
,
Patricia M. LoRusso
,
+14 authors
J. Schellens
2012
Corpus ID: 72746289
The family of fibroblast growth factors (FGFs) and FGF receptors (FGFRs) plays a critical role in cell proliferation and survival…
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2008
2008
Synthesis and characterization of DNA adducts from the HIV reverse transcriptase inhibitor nevirapine.
A. Antunes
,
Mariana P. Duarte
,
+4 authors
M. Marques
Chemical Research in Toxicology
2008
Corpus ID: 25858298
Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor used against the human immunodeficiency virus type 1 (HIV-1…
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Highly Cited
2004
Highly Cited
2004
Tumor Cell and Endothelial Cell Therapy of Oral Cancer by Dual Tyrosine Kinase Receptor Blockade
O. Yiğitbaşı
,
M. Younes
,
+6 authors
J. Myers
Cancer Research
2004
Corpus ID: 16845973
Expression of the epidermal growth factor (EGF) and activation of its receptor (EGFR), a tyrosine kinase, are associated with…
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2004
2004
K579, a slow-binding inhibitor of dipeptidyl peptidase IV, is a long-acting hypoglycemic agent.
K. Takasaki
,
M. Iwase
,
+4 authors
K. Higo
European Journal of Pharmacology
2004
Corpus ID: 30000740
Highly Cited
2002
Highly Cited
2002
1-[2-[(5-Cyanopyridin-2-yl)amino]ethylamino]acetyl-2-(S)-pyrrolidinecarbonitrile: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.
E. B. Villhauer
,
J. Brinkman
,
+6 authors
T. Hughes
Journal of Medicinal Chemistry
2002
Corpus ID: 8966102
Dipeptidyl peptidase IV (DPP-IV) inhibition has the potential to become a valuable therapy for type 2 diabetes. We report the…
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Highly Cited
2002
Highly Cited
2002
Dipeptidyl peptidase IV inhibition improves impaired glucose tolerance in high-fat diet-fed rats: study using a Fischer 344 rat substrain deficient in its enzyme activity.
H. Mitani
,
M. Takimoto
,
T. Hughes
,
M. Kimura
Japanese Journal of Pharmacology
2002
Corpus ID: 25468790
This study was performed to determine the effects of a high-fat diet on glucose metabolism after an oral glucose challenge in…
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2002
2002
Pharmacological profile of a novel phosphodiesterase 4 inhibitor, 4-(8-benzo[1,2,5]oxadiazol-5-yl-[1,7]naphthyridin-6-yl)-benzoic acid (NVP-ABE171), a 1,7-naphthyridine derivative, with anti…
A. Trifilieff
,
D. Wyss
,
C. Walker
,
L. Mazzoni
,
R. Hersperger
Journal of Pharmacology and Experimental…
2002
Corpus ID: 15864901
We investigated the pharmacology of a new class of phosphodiesterase 4 (PDE4) inhibitor, 6,8-disubstituted 1,7-naphthyridines, by…
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1998
1998
The pharmacokinetics of combination therapy with nelfinavir plus nevirapine
C. Merry
,
M. Barry
,
+5 authors
D. Back
AIDS (London)
1998
Corpus ID: 33297628
Objective:To investigate the pharmacokinetics of nelfinavir (NFV) administered alone and in combination with nevirapine (NVP) to…
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