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NUP98 wt Allele

Known as: NUP96 Gene, NUP98, Nucleoporin, 98-kD wt Allele 
Human NUP98 wild-type allele is located in the vicinity of 11p15.5 and is approximately 123 kb in length. This allele, which encodes nuclear pore… 
National Institutes of Health

Related topics

Related topics

10 relations
11p15Acute lymphocytic leukemiaDocking -molecular interactionHomo sapiens

Broader (1)

NUP98 gene

Papers overview

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Highly Cited
2011
Highly Cited
2011
Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK
Nup98 regulates microtubule dynamics during mitotic spindle assembly by opposing the depolymerizing kinesin, MCAK. The Nup98 C… 
2005
2005
Overexpression of HOXB4 confers a myelo-erythroid differentiation delay in vitro
protein may act as an oncogenic transcriptor factor, and the same hypothesis may be carried out for NUP98-PRRX2. PRRX2 was… 
2005
2005
HOX genes: not just myeloid oncogenes any more
The study of HOX homeobox genes in leukemia is a growth industry, as exemplified by a paper by Speleman et al in a recent issue… 
2005
2005
Specific monoclonal antibody against the nuclear pore complex protein, nup98.
Nup98 is a component of nuclear pore complexes, which are large protein assemblies embedded in the nuclear envelope. Previous… 
2004
2004
Deletion 6p23 and add(11)(p15) leading to NUP98 translocation in a case of therapy-related atypical chronic myelocytic leukemia transforming to acute myelocytic leukemia.
2003
2003
Human homeobox gene HOXC13 is the partner of NUP98 in adult acute myeloid leukemia with t(11;12)(p15;q13)
The chimeric gene NUP98/HOXC13 was detected in a patient with a de novo acute myeloid leukemia and a t(11;12)(p15;q13… 
2003
2003
Both NUP98/TOP1 and TOP1/NUP98 transcripts are detected in a de novo AML with t(11;20)(p15;q11)
The NUP98 gene is involved in several chromosomal abnormalities associated with acute leukemia. The recurrent t(11;20)(p15;q11… 
2002
2002
Expression of NUP98/TOP1, but not of TOP1/NUP98, in a treatment‐related myelodysplastic syndrome with t(10;20;11)(q24;q11;p15)
The t(11;20)(p15;q11) is a rare but recurrent translocation that so far has been described in only four acute myeloid leukemias… 
2001
2001
The HOXD 11 Gene Is Fused to the NUP 98 Gene in Acute Myeloid Leukemia with t ( 2 ; 11 ) ( q 31 ; p 15 ) 1
The nucleoporin gene, NUP98, has been reported to be fused to seven partner genes in hematological malignancies with 11p15… 
1999
1999
Low frequency of rearrangements of the homeobox gene HOXA9/t(7;11) in adult acute myeloid leukemia
Translocation (7;11)(p15;p15) is uncommon in acute myeloid leukemia (AML) and may have a predilection to occur in Asian patients… 
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