NSC 725776

Known as: NSC-725776, NSC725776 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2016
01220072016

Papers overview

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2016
2016
An HPLC method for the assay of a DNA topoisomerase inhibitor, LMP776 (NSC 725776), has been developed and validated. The stress… (More)
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2016
2016
BACKGROUND DNA topoisomerase I (Top1) is a DNA unwinding protein and the specific target of the camptothecin class of… (More)
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2013
2013
Indenoisoquinolines are the most promising non-campthotecins topoisomerase IB inhibitors. We present an integrated experimental… (More)
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2010
2010
Topoisomerase I (Topo I) is a recognized target for ovarian, lung, and colorectal cancer therapy. The FDA-approved camptothecin… (More)
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2009
2009
Because camptothecins are effective against previously resistant tumors and are the only class of topoisomerase I (Top1… (More)
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Highly Cited
2007
Highly Cited
2007
Camptothecin (CPT) derivatives are effective anticancer drugs, especially against solid tumors. As CPTs are chemically unstable… (More)
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