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NSC 725776

Known as: NSC-725776, NSC725776 
National Institutes of Health

Papers overview

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2016
2016
BackgroundDNA topoisomerase I (Top1) is a DNA unwinding protein and the specific target of the camptothecin class of… 
2013
2013
Indenoisoquinolines are the most promising non-campthotecins topoisomerase IB inhibitors. We present an integrated experimental… 
Highly Cited
2009
Highly Cited
2009
Because camptothecins are effective against previously resistant tumors and are the only class of topoisomerase I (Top1… 
Highly Cited
2007
Highly Cited
2007
Camptothecin (CPT) derivatives are effective anticancer drugs, especially against solid tumors. As CPTs are chemically unstable…