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NSC-118,994

Known as: NSC-118994 
National Institutes of Health

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Inosine Dialdehyde

Papers overview

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Review
1981
Review
1981
Clinical trials with diglycoaldehyde (NSC-118994): review and reasons for withdrawal from clinical trial.
All Phase II studies with diglycoaldehyde with leukemia and solid tumors have been reviewed. The dose schedules employed ranged… 
1978
1978
Cell killing and kinetic effects of diglycolaldehyde on dividing and nondividing mammalian cells in vitro.
The effects of the anticancer drug diglycolaldehyde (NSC-118994) were studied on Chinese hamster ovary cells growing in vitro… 
1977
1977
Metabolism of the dialdehyde derivative of inosine (NSC-118994): transport, distribution and incorporation into RNA of Ehrlich ascites tumor cells.
1976
1976
Protein cross-linking properties of the antitumor agent inosine dialdehyde (NSC-118994).
Inosine dialdehyde (IdA), a new antitumor agent presently undergoing clinical evaluation in man, possesses two aldehyde groups… 
1976
1976
Pharmacologic disposition of inosine dialdehyde (NSC-118994) in mice, rats, dogs, and monkeys.
The pharmacologic disposition of inosine dialdehyde (IdA) was studied in mice, rats, dogs, and monkeys. 14C-IdA was utilized to… 
1976
1976
Pharmacologic disposition of inosine dialdehyde (NSC-118994) in mice, rats, dogs, and monkeys.
: The pharmacologic disposition of inosine dialdehyde (IdA) was studied in mice, rats, dogs, and monkeys. 14C-IdA was utilized to… 
1975
1975
Clinical phase I trial of inosine dialdehyde (NSC-118994).
An initial clinical phase I trial of inosine dialdehyde has been carried out in 40 patients at dose levels of 30-4000 mg/m2 for 5… 
1975
1975
Chemical assay for the antitumor agent inosine dialdehyde (NSC-118994) in biologic fluids.
Inosine dialdehyde, an antitumor agent highly active against several murine tumors, ispresently undergoing clinical trial for… 
1975
1975
Chemical assay for the antitumor agent inosine dialdehyde (NSC-118994) in biologic fluids.
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