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NS 398

Known as: NS-398 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Cardiovascular , Pulmonary and Renal Pathology Cooperation of TLR 2 with MyD 88 , PI 3 K , and Rac 1 in Lipoteichoic Acid – Induced cPLA 2 / COX-2 – Dependent Airway Inflammatory Responses
From the Department of Physiology and Pharmacology,* Chang Gung University, Kwei-San, Tao-Yuan; the Department of Nursing… 
2010
2010
Aspirin induces apoptosis in YD-8 human oral squamous carcinoma cells through activation of caspases, down-regulation of Mcl-1, and inactivation of ERK-1/2 and AKT.
Highly Cited
2007
Highly Cited
2007
Intrathecally administered COX-2 but not COX-1 or COX-3 inhibitors attenuate streptozotocin-induced mechanical hyperalgesia in rats.
Highly Cited
2003
Highly Cited
2003
Cyclooxygenase-2 mediates interleukin-6 upregulation by vomitoxin (deoxynivalenol) in vitro and in vivo.
Highly Cited
2002
Highly Cited
2002
Role for both spinal cord COX-1 and COX-2 in maintenance of mechanical hypersensitivity following peripheral nerve injury
Highly Cited
2002
Highly Cited
2002
NS‐398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines
Cyclooxygenase 2 (COX‐2) has been suggested to be associated with liver carcinogenesis. Several reports have shown that NSAIDs… 
Highly Cited
2002
Highly Cited
2002
Nitric oxide synergistically potentiates interleukin-1β-induced increase of cyclooxygenase-2 mRNA levels, resulting in the facilitation of substance P release from primary afferent neurons…
Highly Cited
2001
Highly Cited
2001
Role of cyclopentenone prostaglandins in rat carrageenin pleurisy
Highly Cited
2000
Highly Cited
2000
Coordinate up- and down-regulation of glutathione-dependent prostaglandin E synthase and cyclooxygenase-2 in A549 cells. Inhibition by NS-398 and leukotriene C4.
Recently, a microsomal protein with 38% sequence identity to microsomal glutathione S-transferase 1 was shown to constitute an… 
Highly Cited
1997
Highly Cited
1997
Tumor necrosis factor-alpha promotes sustained cyclooxygenase-2 expression: attenuation by dexamethasone and NSAIDs.
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