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NRXN2 gene

Known as: Neurexin 2 Gene, NRXN2, neurexin 2 
This gene may play a role in cell adhesion.
National Institutes of Health

Related topics

Related topics

6 relations
Cell AdhesionLigand BindingNeurexin-2, humanSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Neurexins and neuropsychiatric disorders
Highly Cited
2015
Highly Cited
2015
Genetic targeting of NRXN2 in mice unveils role in excitatory cortical synapse function and social behaviors
Human genetics has identified rare copy number variations and deleterious mutations for all neurexin genes (NRXN1-3) in patients… 
Highly Cited
2015
Highly Cited
2015
Heterozygous Deletion of α-Neurexin I or α-Neurexin II Results in Behaviors Relevant to Autism and Schizophrenia
The neurexins are a family of presynaptic cell adhesion molecules. Human genetic studies have found heterozygous deletions… 
Highly Cited
2014
Highly Cited
2014
SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy.
Spinal muscular atrophy (SMA) is a progressive neurodegenerative disease affecting lower motor neurons. SMA is caused by… 
Highly Cited
2012
Highly Cited
2012
Rare deletions at the neurexin 3 locus in autism spectrum disorder.
Highly Cited
2011
Highly Cited
2011
Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia
Growing genetic evidence is converging in favor of common pathogenic mechanisms for autism spectrum disorders (ASD), intellectual… 
Highly Cited
2009
Highly Cited
2009
Disruption of the neurexin 1 gene is associated with schizophrenia.
Deletions within the neurexin 1 gene (NRXN1; 2p16.3) are associated with autism and have also been reported in two families with… 
Highly Cited
2009
Highly Cited
2009
Prenatal exposure to valproic acid leads to reduced expression of synaptic adhesion molecule neuroligin 3 in mice
Highly Cited
2009
Highly Cited
2009
LAD-1/variant syndrome is caused by mutations in FERMT3.
Leukocyte adhesion deficiency-1/variant (LAD1v) syndrome presents early in life and manifests by infections without pus formation… 
2007
2007
Ca2+ -dependent splicing of neurexin IIalpha.
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