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Abundance and Significance of Neuroligin-1 and Neurexin II in the Enteric Nervous System of Embryonic Rats
Neuroligin-1 and neurexin II were both expressed in the ENS and have temporal correlation with the development of ENS, during which neuronal intestinal malformations (NIM) may occur due to their disruptions and consequent abnormal ENS development. Expand
Aberrant Distributions of Collagen I, III and IV in Hirschsprung's Disease.
  • N. Gao, J. Wang, +6 authors Aiwu Li
  • Medicine
  • Journal of pediatric gastroenterology and…
  • 13 January 2020
Col I and Col III are decreased and Col IV is increased in the distal colon of HSCR patients, and the relative levels of these collagens in aganglionic, transitional, and ganglionic colon segments are examined. Expand
Effect of Neuroligin1 and Neurexin1 on the Colonic Motility in a Mouse Model of Neuronal Intestinal Dysplasia
NL1 and NX1 are closely related to the colonic motility through their effects of targeting the formation of glutamatergic synapses and may be involved in the pathogenesis of NID. Expand
Increased Fibronectin Impairs the Function of Excitatory/Inhibitory Synapses in Hirschsprung Disease
Results are consistent with the idea that the etiology of HSCR involves aberrant overexpression of FN, which may impair synaptic function and enteric nervous system development, leading to motor dysfunction of intestinal muscles. Expand
Expression and significance of NeurexinIIin enteric nervous system of rats at different embryonic days
NeurexinⅡ may have temporal correlation with the development of ENS during which neuronal intestinal malformations occur due to dysplasia, and its expression level increased gradually from embryonic day 16 to newborns within 24 h. Expand
Comparative Clinical Study Between Modified Ureteral Orthotopic Reimplantation and Cohen Method Under Pneumovesicum in Pediatric Patients With Hydroureteronephrosis
The authors' modified ureteral orthotopic reimplantation technique under pneumovesicum can be safely and effectively performed, achieving a high success rate that is equivalent to that obtained through the Cohen technique underneumovesicum. Expand
The inverse relationship between fibronectin and neuroligins in the embryonic rat colon
The studies showed that there were downregulatory effects between FN and the NLs in the embryonic rat colon and different cell lines, indicating that FN and NLs could directly regulate each other, and there is a negative linear correlation between them. Expand