Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

NR3C1 protein, human

Known as: Nuclear Receptor Subfamily 3 Group C Member 1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) protein, human, Glucocorticoid Receptor 
Glucocorticoid receptor (777 aa, ~86 kDa) is encoded by the human NR3C1 gene. This protein plays a role in both chromatin remodeling and… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
The estrogen receptor (ER), glucocorticoid receptor (GR), and forkhead box protein 1 (FoxA1) are significant factors in breast… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2013
Highly Cited
2013
BACKGROUND Stress-related disorders (e.g., depression) are associated with hypothalamic-pituitary-adrenocortical axis… Expand
Is this relevant?
Highly Cited
2011
Highly Cited
2011
ABSTRACT Glucocorticoids are stress hormones that maintain homeostasis through gene regulation mediated by nuclear receptors. We… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2008
Highly Cited
2008
ABSTRACT Aberrant glycogen synthase kinase 3β (GSK-3β) activity is associated with the progression of several pathological… Expand
Is this relevant?
Highly Cited
2008
Highly Cited
2008
The generality and spectrum of chromatin-remodeling requirements for nuclear receptor function are unknown. We have characterized… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Introduction: Evidence is accumulating that the regular performance of exercise is beneficial for stress coping. However, the… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Environmental constraints during early life result in phenotypic changes that can be associated with increased disease risk in… Expand
  • table 1
  • table 3
  • figure 1
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Cytochrome P450 (P450) enzymes play important roles in the metabolism of endogenous and xenobiotic substrates in humans. CYP2C8… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Glucocorticoids are secreted from the adrenal glands and act as a peripheral effector of the hypothalamic-pituitary-adrenal axis… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Potential mechanisms underlying prenatal programming of hypertension in adult life were investigated using a rat model in which… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?