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NR3C1 protein, human

Known as: Nuclear Receptor Subfamily 3 Group C Member 1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) protein, human, Glucocorticoid Receptor 
Glucocorticoid receptor (777 aa, ~86 kDa) is encoded by the human NR3C1 gene. This protein plays a role in both chromatin remodeling and… 
National Institutes of Health

Related topics

Related topics

29 relations
Androgen Receptor Regulation PathwayBiologic DevelopmentCell Differentiation processCell Nucleus

Broader (1)

Glucocorticoid Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Post-traumatic stress avoidance is attenuated by corticosterone and associated with brain levels of steroid receptor co-activator-1 in rats
Abstract Individuals with post-traumatic stress disorder (PTSD) avoid trauma-related stimuli and exhibit blunted hypothalamic… 
Highly Cited
2012
Highly Cited
2012
Prenatal nicotine exposure induced a hypothalamic-pituitary-adrenal axis-associated neuroendocrine metabolic programmed alteration in intrauterine growth retardation offspring rats.
Highly Cited
2004
Highly Cited
2004
Expression of estrogen receptor-alpha and -beta, glucocorticoid receptor, and progesterone receptor genes in human embryonic stem cells and embryoid bodies.
Human embryonic stem cells (hESCs) have the potential to differentiate into various cell types, and the three germ layers in vivo… 
Highly Cited
2003
Highly Cited
2003
Dissociation of steroid receptor coactivator 1 and nuclear receptor corepressor recruitment to the human glucocorticoid receptor by modification of the ligand-receptor interface: the role of tyrosine…
Within the human glucocorticoid receptor (GR) steroid binding pocket, tyrosine 735 makes hydrophobic contact with the steroid D… 
Highly Cited
1996
Highly Cited
1996
Long‐Term Selective Down‐Regulation of Brain Glucocorticoid Receptors after Neonatal Dexamethasone Treatment in Rats
The development of corticosteroid receptors may be permanently modified by perinatal hormonal influences. Changes in binding… 
Review
1986
Review
1986
Glucocorticoid receptors and glucocorticoid resistance in human leukemia in vivo and in vitro.
Clinical measurements quantitating glucocorticoid receptor sites in leukemic blasts may give useful prognostic information. In… 
Highly Cited
1985
Highly Cited
1985
Molybdate-stabilized glucocorticoid receptor: evidence for a receptor heteromer.
The composition of the molybdate-stabilized glucocorticoid receptor (GR) complex has been investigated with a monoclonal antibody… 
Review
1984
Review
1984
Glucocorticoid receptors and steroid sensitivity in normal and neoplastic human lymphoid tissues: a review.
The determination of estrogen and progesterone receptors in breast cancer has been shown to be useful in predicting the response… 
Highly Cited
1981
Highly Cited
1981
Glucocorticoid receptors in adult acute lymphoblastic leukemia.
Glucocorticoid receptors were studied in leukemic cells from 14 newly diagnosed adults with acute lymphoblastic leukemia… 
Highly Cited
1977
Highly Cited
1977
Glucocorticoid receptors in purified subpopulations of human peripheral blood lymphocytes.
On the premise that the differential effects of glucocorticoids on various aspects of the immune response may be mediated by… 
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