Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

NPR1 protein, human

Known as: EC 4.6.1.2, Atrionatriuretic Peptide Receptor, Type A, Atrial Natriuretic Peptide Receptor Type A 
Atrial natriuretic peptide receptor 1 (1061 aa, ~119 kDa) is encoded by the human NPR1 gene. This protein plays a role in both guanylate cyclase… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Cardiac atrial natriuretic peptide (ANP) regulates arterial blood pressure, moderates cardiomyocyte growth, and stimulates… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2010
Highly Cited
2010
Rationale: Atrial and brain natriuretic peptides (ANP and BNP, respectively) exert antihypertrophic effects in the heart via… Expand
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Review
2007
Review
2007
The natriuretic peptides (NPs) are a group of peptide hormones that play important roles in the control of renal, cardiovascular… Expand
  • figure 1
  • figure 2
Highly Cited
2005
Highly Cited
2005
Mice carrying a targeted disruption of the Npr1 gene (coding for guanylyl cyclase/natriuretic peptide receptor A (NPRA)) exhibit… Expand
  • table I
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
2002
Highly Cited
2002
Background—Guanylyl cyclase (GC)-A, a natriuretic peptide receptor, lowers blood pressure and inhibits the growth of cardiac… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Highly Cited
2002
Highly Cited
2002
Objective: To investigate how permanent inhibition of guanylyl cyclase A receptor (GC-A) affects cardiac function. Methods… Expand
Highly Cited
2001
Highly Cited
2001
Mice lacking natriuretic peptide receptor A (NPRA) have marked cardiac hypertrophy and chamber dilatation disproportionate to… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
1997
Highly Cited
1997
Natriuretic peptides, produced in the heart, bind to the natriuretic peptide receptor A (NPRA) and cause vasodilation and… Expand
  • figure 1
  • figure 3
  • figure 2
  • table 1
  • figure 4
Highly Cited
1992
Highly Cited
1992
Atrial natriuretic peptide (ANP) binds to the guanylyl cyclase-A (GC-A) receptor found in tissues such as the kidney and adrenal… Expand
Highly Cited
1992
Highly Cited
1992
  • D. Lowe
  • Biochemistry
  • 1992
  • Corpus ID: 11051
The human natriuretic peptide receptor-A (NPR-A) guanylyl cyclase is specifically activated to synthesize cGMP by binding of… Expand