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NPR1 protein, human

Known as: EC 4.6.1.2, Atrionatriuretic Peptide Receptor, Type A, Atrial Natriuretic Peptide Receptor Type A 
Atrial natriuretic peptide receptor 1 (1061 aa, ~119 kDa) is encoded by the human NPR1 gene. This protein plays a role in both guanylate cyclase… Expand
National Institutes of Health

Papers overview

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2017
2017
Significance Atrial fibrillation is the most frequent cardiac arrhythmia and is a major cause of stroke. Recently, it has been… Expand
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2011
2011
Cardiac atrial natriuretic peptide (ANP) regulates arterial blood pressure, moderates cardiomyocyte growth, and stimulates… Expand
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2010
2010
Atrial natriuretic peptide (ANP), via its guanylyl cyclase A (GC-A) receptor and intracellular guanosine 3',5'-cyclic… Expand
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2004
2004
OBJECTIVE Atrial (ANP) and B-type natriuretics peptides (BNP) via their guanylyl cyclase-A (GC-A) receptor not only regulate… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Guanylyl cyclase (GC)-A, a natriuretic peptide receptor, lowers blood pressure and inhibits the growth of cardiac… Expand
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Highly Cited
2002
Highly Cited
2002
OBJECTIVE To investigate how permanent inhibition of guanylyl cyclase A receptor (GC-A) affects cardiac function. METHODS… Expand
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2002
2002
OBJECTIVE The natriuretic peptides (NPs), atrial (ANP), B-type (BNP), and C-type (CNP) natriuretic peptides as well as their… Expand
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Highly Cited
2001
Highly Cited
2001
Mice lacking natriuretic peptide receptor A (NPRA) have marked cardiac hypertrophy and chamber dilatation disproportionate to… Expand
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Highly Cited
1997
Highly Cited
1997
Natriuretic peptides, produced in the heart, bind to the natriuretic peptide receptor A (NPRA) and cause vasodilation and… Expand
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1992
1992
The human natriuretic peptide receptor-A (NPR-A) guanylyl cyclase is specifically activated to synthesize cGMP by binding of… Expand
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