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Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis.
BACKGROUND & AIMS Patients with cirrhosis hospitalized for an acute decompensation (AD) and organ failure are at risk for imminent death and considered to have acute-on-chronic liver failure (ACLF).Expand
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Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis
Hepatorenal syndrome (HRS) is a serious complication of end-stage liver disease, occurring mainly in patients with advanced cirrhosis and ascites, who have marked circulatory dysfunction,1 as well asExpand
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Diagnosis and management of acute kidney injury in patients with cirrhosis: revised consensus recommendations of the International Club of Ascites.
Diagnosis and management of acute kidney injury in patients with cirrhosis: Revised consensus recommendations of the International Club of Ascites Paolo Angeli1,⇑, Pere Ginès, Florence Wong, MauroExpand
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Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis
Objectives To propose an improvement on the current classification of renal dysfunction in cirrhosis. Clinicians caring for patients with cirrhosis recognize that the development of renal dysfunctionExpand
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Role of Kupffer cells in host defense and liver disease
Abstract: Kupffer cells (KC) constitute 80–90% of the tissue macrophages present in the body. They reside within the lumen of the liver sinusoids, and are therefore constantly exposed to gut‐derivedExpand
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Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure.
BACKGROUND & AIMS Acute-on-chronic liver failure (ACLF) is a frequent syndrome (30% prevalence), characterized by acute decompensation of cirrhosis, organ failure(s) and high short-term mortality.Expand
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Spontaneous bacterial peritonitis: recent guidelines and beyond
Spontaneous bacterial peritonitis (SBP) is the most frequent and life-threatening infection in patients with liver cirrhosis requiring prompt recognition and treatment. It is defined by the presenceExpand
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Clinical Course of acute‐on‐chronic liver failure syndrome and effects on prognosis
Acute‐on‐chronic liver failure (ACLF) is characterized by acute decompensation (AD) of cirrhosis, organ failure(s), and high 28‐day mortality. We investigated whether assessments of patients atExpand
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