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NOBOX gene

Known as: NEWBORN OVARY HOMEOBOX, MOUSE, HOMOLOG OF, Og2x, NOBOX 
National Institutes of Health

Papers overview

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2017
2017
A homozygous NOBOX truncating variant causes defective transcriptional activation and leads to primary ovarian insufficiency
STUDY QUESTION Does a novel homozygous NOBOX truncating variant, identified in whole exome sequencing (WES) of patients with… 
Highly Cited
2015
Highly Cited
2015
Lhx8 regulates primordial follicle activation and postnatal folliculogenesis
BackgroundThe early stages of ovarian follicle formation—beginning with the breakdown of germ cell cysts and continuing with the… 
Highly Cited
2007
Highly Cited
2007
NOBOX homeobox mutation causes premature ovarian failure.
NOBOX (newborn ovary homeobox gene) is an oocyte-specific homeobox gene that plays a critical role in early folliculogenesis and… 
Highly Cited
2007
Highly Cited
2007
Germline stem cells and neo-oogenesis in the adult human ovary.
Highly Cited
2006
Highly Cited
2006
Sohlh2 is a germ cell-specific bHLH transcription factor.
Highly Cited
2006
Highly Cited
2006
Characterization of NOBOX DNA Binding Specificity and Its Regulation of Gdf9 and Pou5f1 Promoters*
Nobox (newborn ovary homeobox gene) deficiency disrupts early folliculogenesis and the expression of oocyte-specific genes in… 
Highly Cited
2004
Highly Cited
2004
NOBOX Deficiency Disrupts Early Folliculogenesis and Oocyte-Specific Gene Expression
Primordial ovarian follicles in mice form when somatic cells surround individual oocytes. We show that lack of Nobox, an oocyte… 
Highly Cited
2002
Highly Cited
2002
Overexpression of Phex in Osteoblasts Fails to Rescue the Hyp Mouse Phenotype*
Inactivating mutations of Phex, a phosphate-regulating endopeptidase, cause hypophosphatemia and impaired mineralization in X… 
Highly Cited
1999
Highly Cited
1999
Characterization of Osf1, an Osteoblast-specific Transcription Factor Binding to a Critical cis-acting Element in the MouseOsteocalcin Promoters*
To elucidate the mechanisms of osteoblast-specific gene expression we are studying the regulation ofosteocalcin, the most… 
Highly Cited
1997
Highly Cited
1997
1,25-Dihydroxyvitamin D3 Inhibits Osteocalcin Expression in Mouse through an Indirect Mechanism*
1,25-Dihydroxyvitamin D3 (1,25-(OH)2D3), a key regulator of mineral metabolism, regulates the expression of several genes that… 
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