NOBOX gene

PurposeTo understand the mechanism of premature ovarian failure (POF).MethodsThe ultrastructural (electron microscopy) analysis… Expand

Abstract Lhx8 is a member of the LIM-homeobox transcription factor family and preferentially expressed in oocytes and germ cells… Expand

NOBOX (newborn ovary homeobox gene) is an oocyte-specific homeobox gene that plays a critical role in early folliculogenesis and… Expand

Nobox (newborn ovary homeobox gene) deficiency disrupts early folliculogenesis and the expression of oocyte-specific genes in… Expand

Nobox is a homeobox gene that is preferentially expressed in the oocytes and is essential for folliculogenesis and the regulation… Expand

Primordial ovarian follicles in mice form when somatic cells surround individual oocytes. We show that lack of Nobox, an oocyte… Expand

To identify novel genes involved in early mammalian folliculogenesis, we used the Unigene collection of mouse cDNA libraries to… Expand

Inactivating mutations of Phex, a phosphate-regulating endopeptidase, cause hypophosphatemia and impaired mineralization in X… Expand

To elucidate the mechanisms of osteoblast-specific gene expression we are studying the regulation of osteocalcin, the most… Expand

1,25-Dihydroxyvitamin D3 (1,25-(OH)2D3), a key regulator of mineral metabolism, regulates the expression of several genes that… Expand