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NK 121

Known as: NK-121, NK121 
National Institutes of Health

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4 relations

Broader (2)

Antineoplastic AgentsCarboplatin
CI 973analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Heat enhances the cytotoxicity ofcis-diamminedichloroplatinum(II) and its analoguescis-1,1-cyclobutane-dicarboxylato(2R)-2-methyl-1,4-butanediammineplatinum(II) andcis-diammine(glycolato)platinum in…
Abstractcis-1,1-Cyclobutanedicarboxylato(2R)-2-methyl-1,4-butanediammineplatinum(II) (NK121) andcis-diammine(glycolato)platinum… 
1996
1996
Interaction of cis-diamminedichloro-platinum(II) and its analogues cis-1,1- cyclobutanedicarboxylato(2R)-2-methyl-1,4-butanediammineplatinum(II) and cis-diammine(glycolato)platinum with hyperthermia…
The interaction of cis-1,1-cyclobutanedicarboxylato(2R)-2-methyl-1,4- butanediammineplatinum(II) (NK121) and cis-diammine… 
1994
1994
Chemotherapy with [SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato(2-)](2- methyl-1,4-butanediamine-N,N')platinum (CI-973, NK121) in combination with standard agents against murine tumors in vivo.
[SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato(2-)](2-methyl-1,4- butane-diamine-N,N')platinum (CI-973) is a cisplatin analogue that… 
1993
1993
Cell cycle perturbations of platinum derivatives on two ovarian cancer cell lines.
Cisplatin continues to be one of the most commonly used cytotoxic agent. Problems of drug resistance and nephrotoxicity have… 
1993
1993
Hyperthermic enhancement of cell killing by five platinum complexes in human malignant melanoma cells grown as monolayer cultures and multicellular spheroids.
1993
1993
Comparison of cytotoxicity and cell kinetic perturbations of 5 platinum compounds in gynecologic cancer cell-lines.
New platinum derivatives were synthesized to overcome problems of cisplatin resistance and nephrotoxicity. Five platinum… 
Review
1993
Review
1993
[Cisplatinum compounds].
New cisplatinum derivatives of 254-S, DWA2114R and NK121 developed in Japan were reviewed. These three compounds have less… 
1992
1992
Optimal administration schedules of the newly synthesized platinum analog nk121 and bleomycin analog nk313 in nude mice with squamous cell carcinoma
To determine the optimal administration schedules of the newly synthesized, less nephrotoxic platinum analog NK121 and less… 
1991
1991
Clinical Studies with Cisplatin Analogues, 254-S, DWA2114R and NK121
Development of CDDP analogues in Japan has been concerned with second generation analogues, especially which need no hydration or… 
1991
1991
[The characteristics of nasopharyngeal carcinoma cell strain against chemotherapeutic agents and cytokines].
The closed relationship between nasopharyngeal carcinoma (NPC) and Epstein-Barr virus (EBV) has been pointed out. However, it… 
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