NIP 121

Known as: 2-Piperidinone, 1-(7,8-dihydro-7-hydroxy-6,6-dimethyl-6H-pyrano(2,3-f)-2,1,3-benzoxadiazol-8-yl)-, trans-(+)-, NIP-121 
 
National Institutes of Health

Papers overview

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1999
1999
To investigate whether chronic hypoxia affects endothelin-B (ETB) receptor-mediated pulmonary vasodilation, we compared the… Expand
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1998
1998
The effects of K+ channel openers, NIP-121, cromakalim, and pinacidil, on isolated myocardium and aorta were investigated at two… Expand
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1996
1996
We investigated the effect of NIP-121, a novel ATP-sensitive K+ channel opener, on myocardial damage during ischemia/reperfusion… Expand
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1995
1995
Myocardial effects of NIP-121, a novel compound with potent vasorelaxant activity, were examined in comparison with those of… Expand
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1995
1995
The effects of potassium channel openers NIP-121 ((+)-7,8-dihydro-6,6-dimethyl-7-hydroxy-8-(2-oxo-piperidine-1-yl)-6H- pyrano[2,3… Expand
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1994
1994
We examined the effects of NIP-121, a potassium channel opener, on KCl- and norepinephrine (NE)-induced contraction, the phasic… Expand
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1993
1993
To determine if NIP-121, a new antihypertensive agent with K+ channel-opening activity, would be an effective vasodilator in… Expand
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1991
1991
We have investigated the relaxant effect of the potassium channel openers, NIP-121 and cromakalim, on spontaneous and spasmogen… Expand
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1991
1991
The antihypertensive effects of NIP-121, a novel potassium channel opener, were examined in comparison with cromakalim and its… Expand
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1991
1991
A novel compound, NIP-121, cromakalim and nicorandil caused concentration-dependent relaxation of rat aortas precontracted with… Expand
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