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NIP 121

Known as: 2-Piperidinone, 1-(7,8-dihydro-7-hydroxy-6,6-dimethyl-6H-pyrano(2,3-f)-2,1,3-benzoxadiazol-8-yl)-, trans-(+)-, NIP-121 
 
National Institutes of Health

Papers overview

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1999
1999
To investigate whether chronic hypoxia affects endothelin-B (ETB) receptor-mediated pulmonary vasodilation, we compared the… Expand
1996
1996
We investigated the effect of NIP-121, a novel ATP-sensitive K+ channel opener, on myocardial damage during ischemia/reperfusion… Expand
1995
1995
Myocardial effects of NIP-121, a novel compound with potent vasorelaxant activity, were examined in comparison with those of… Expand
1995
1995
The effects of potassium channel openers NIP-121 ((+)-7,8-dihydro-6,6-dimethyl-7-hydroxy-8-(2-oxo-piperidine-1-yl)-6H- pyrano[2,3… Expand
1994
1994
We examined the effects of NIP-121, a potassium channel opener, on KCl- and norepinephrine (NE)-induced contraction, the phasic… Expand
Highly Cited
1993
Highly Cited
1993
To determine if NIP-121, a new antihypertensive agent with K+ channel-opening activity, would be an effective vasodilator in… Expand
1993
1993
1 We have investigated the effect of the potassium channel opener, NIP‐121, on contraction elicited by melittin (a phospholipase… Expand
1992
1992
1 The effect of the potassium channel openers, NIP‐121 and cromakalim, on agonist‐induced relaxation of the guinea‐pig isolated… Expand
1991
1991
We have investigated the relaxant effect of the potassium channel openers, NIP-121 and cromakalim, on spontaneous and spasmogen… Expand
1991
1991
The antihypertensive effects of NIP-121, a novel potassium channel opener, were examined in comparison with cromakalim and its… Expand