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NEXN gene

Known as: nexilin, NEXILIN, RAT, HOMOLOG OF, nexilin F-actin binding protein 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Stunting Among Under 5-Year-Olds in Nepal: Trends and Risk Factors
Introduction The nutritional status in the first 5 years of life has lifelong and inter-generational impacts on individual’s… 
2019
2019
Whole genome and transcriptome sequencing of post-mortem cardiac tissues from sudden cardiac death victims identifies a gene regulatory variant in NEXN
Sudden cardiac death (SCD) is a major public health problem and constitutes a diagnostic and preventive challenge in forensic… 
2016
2016
The nuclear pore protein Nup153 associates with chromatin and regulates cardiac gene expression in dystrophic mdx hearts.
Aims Beyond the control of nuclear-cytoplasmic trafficking nucleoporins regulate gene expression and are involved in cardiac… 
Highly Cited
2015
Highly Cited
2015
Diagnosis, prevalence, and screening of familial dilated cardiomyopathy
Introduction: Dilated cardiomyopathy (DCM) is the most common cardiomyopathy and occurs often in families. As an inherited… 
2013
2013
NEXN Is a Novel Susceptibility Gene for Coronary Artery Disease in Han Chinese
Coronary artery disease (CAD) is the leading cause of death and disability in the world. Genome-wide association studies have… 
2013
2013
Nexilin, a Cardiomyopathy-Associated F-Actin Binding Protein, Binds and Regulates IRS1 Signaling in Skeletal Muscle Cells
Insulin stimulates glucose uptake through a highly organized and complex process that involves movement of the glucose… 
Highly Cited
2009
Highly Cited
2009
Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy
Z-disks, the mechanical integration sites of heart and skeletal muscle cells, link anchorage of myofilaments to force reception… 
Highly Cited
2005
Highly Cited
2005
Patterns of Gene Expression Differentially Regulated by Platelet-derived Growth Factor and Hypertrophic Stimuli in Vascular Smooth Muscle Cells
In vascular smooth muscle cells (VSMC), platelet-derived growth factor (PDGF) suppresses expression of multiple smooth muscle… 
Highly Cited
1998
Highly Cited
1998
Nexilin: A Novel Actin Filament-binding Protein Localized at Cell–Matrix Adherens Junction
We isolated two novel actin filament (F-actin)–binding proteins from rat brain and rat 3Y1 fibroblast. They were splicing… 
1997
1997
Nuclear factor Y controls the basal transcription activity of the mouse platelet-derived-growth-factor beta-receptor gene.
To determine the regulatory mechanism of the expression of the mouse platelet-derived growth factor (PDGF) beta-receptor gene, a… 
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