NCSTN gene

Known as: KIAA0253, NCSTN, ANTERIOR PHARYNX DEFECTIVE 2, C. ELEGANS, HOMOLOG OF 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Gamma-secretase mediates the final proteolytic cleavage, which liberates amyloid beta-peptide (Abeta), the major component of… (More)
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Highly Cited
2005
Highly Cited
2005
gamma-secretase catalyzes the intramembrane cleavage of amyloid precursor protein (APP) and Notch after their extracellular… (More)
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Highly Cited
2005
Highly Cited
2005
Macroautophagy, which is a lysosomal pathway for the turnover of organelles and long-lived proteins, is a key determinant of cell… (More)
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Highly Cited
2004
Highly Cited
2004
In Alzheimer's disease (AD), the neuropathologic hallmarks of beta-amyloid deposition and neurofibrillary degeneration are… (More)
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Highly Cited
2004
Highly Cited
2004
Mitochondria are central in the regulation of cell death. Apart from providing the cell with ATP, mitochondria also harbor… (More)
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Highly Cited
2003
Highly Cited
2003
Alzheimer's disease is associated with increased production and aggregation of amyloid-beta (Abeta) peptides. Abeta peptides are… (More)
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Highly Cited
2003
Highly Cited
2003
Alzheimer's disease is associated with increased production and aggregation of amyloid-β (Aβ) peptides. Aβ peptides are derived… (More)
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Highly Cited
2003
Highly Cited
2003
mechanism needs further scrutiny, -Secretase may -Secretase cleaves the Amyloid Precursor Protein therefore indeed be considered… (More)
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Highly Cited
2002
Highly Cited
2002
Early embryonic cells in Caenorhabditis elegans embryos interact through a signaling pathway closely related to the Notch… (More)
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Highly Cited
2002
Highly Cited
2002
Presenilin heterodimers apparently contain the active site of gamma-secretase, a polytopic aspartyl protease involved in the… (More)
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