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NCS1 gene

Known as: NCS-1, FREQ, FREQUENIN, DROSOPHILA, HOMOLOG OF 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Origin, diversification and substrate specificity in the family of NCS1/FUR transporters
NCS1 proteins are H+/Na+ symporters specific for the uptake of purines, pyrimidines and related metabolites. In this article, we… 
Review
2015
Review
2015
Sense and specificity in neuronal calcium signalling☆
2015
2015
Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions
Background: Neuronal calcium sensor-1 (NCS-1) is a Ca2+-binding protein that interacts with neuronal proteins. Results: NCS-1… 
2012
2012
Modeling, Substrate Docking, and Mutational Analysis Identify Residues Essential for the Function and Specificity of a Eukaryotic Purine-Cytosine NCS1 Transporter*
Background: The purine-cytosine FcyB transporter is a prototype member of the NCS1 family. Results: Using homology modeling… 
Review
2012
Review
2012
Molecular structure and target recognition of neuronal calcium sensor proteins
Neuronal calcium sensor (NCS) proteins, a sub-branch of the EF-hand superfamily, are expressed in the brain and retina where they… 
Highly Cited
2010
Highly Cited
2010
Paclitaxel accelerates spontaneous calcium oscillations in cardiomyocytes by interacting with NCS-1 and the InsP3R.
2009
2009
A unique phosphatidylinositol 4-phosphate 5-kinase is activated by ADP-ribosylation factor in Plasmodium falciparum.
Highly Cited
2007
Highly Cited
2007
Chronic exposure to paclitaxel diminishes phosphoinositide signaling by calpain-mediated neuronal calcium sensor-1 degradation
Paclitaxel (Taxol) is a well established chemotherapeutic agent for the treatment of solid tumors, but it is limited in its… 
Highly Cited
2004
Highly Cited
2004
Abnormalities in the dopamine system in schizophrenia may lie in altered levels of dopamine receptor-interacting proteins
Highly Cited
2002
Highly Cited
2002
Differential Use of Myristoyl Groups on Neuronal Calcium Sensor Proteins as a Determinant of Spatio-temporal Aspects of Ca2+ Signal Transduction*
The localizations of three members of the neuronal calcium sensor (NCS) family were studied in HeLa cells. Using hippocalcin-EYFP… 
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