FAQ

NCOA3 wt Allele

Known as: ACTR, CAGH16, p/CIP 
Human NCOA3 wild-type allele in the vicinity of 20q12 is approximately 155 kb in length. This allele, which encodes nuclear receptor coactivator 3… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2015
024619972015

Related topics

Related topics

7 relations
20q12Histone AcetylationHomo sapiensTranscriptional Activation
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Broader (1)

NCOA3 gene

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
NCOA3 wt Allele
Transcriptional Activation
Transcriptional Regulation
Homo sapiens
Histone Acetylation
steroid receptor coactivator AIB1

Papers overview

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2007
2007
Clinical implications of steroid receptor coactivator (SRC)-3 in uterine endometrial cancers.
Estrogen is recognized as a significant modifier in the development, growth and invasion of uterine endometrial cancer. Steroid… (More)
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2006
2006
TNF-α enhances estrogen-induced cell proliferation of estrogen-dependent breast tumor cells through a complex containing nuclear factor-kappa B
Breast tumors are usually classified according to their response to estrogens as hormone-dependent or -independent. In this work… (More)
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2003
2003
The MN1 oncoprotein synergizes with coactivators RAC3 and p300 in RAR-RXR-mediated transcription
The t(12;22) creates an MN1–TEL fusion gene leading to acute myeloid leukemia. The fusion partner TEL (ETV6) is a member of the… (More)
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Highly Cited
2001
Highly Cited
2001
Expression of the nuclear coactivator AIB1 in normal and malignant breast tissue
The gene of the nuclear receptor coactivator AIB1 (amplified in breast cancer 1) is amplified in breast cancer cell lines as well… (More)
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2001
2001
AIB1 enhances estrogen-dependent induction of cyclin D1 expression.
AIB1 was isolated as a gene amplified in breast cancer and encodes a protein that acts as a steroid receptor coactivator. The… (More)
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Highly Cited
2000
Highly Cited
2000
Amplification and over-expression of the AIB1 nuclear receptor co-activator gene in primary gastric cancers.
Our analysis of chromosomal aberrations in primary gastric cancers using comparative genomic hybridization has revealed novel… (More)
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2000
2000
RAC-3 is a NF-kappa B coactivator.
It has been shown that the molecular mechanism by which cytokines and glucocorticoids mutually antagonize their functions… (More)
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Highly Cited
1997
Highly Cited
1997
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer.
Members of the recently recognized SRC-1 family of transcriptional coactivators interact with steroid hormone receptors to… (More)
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Highly Cited
1997
Highly Cited
1997
Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300
We report here the identification of a novel cofactor, ACTR, that directly binds nuclear receptors and stimulates their… (More)
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Highly Cited
1997
Highly Cited
1997
TRAM-1, A novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1.
Nuclear hormone receptors (NRs) are ligand-dependent transcription factors that regulate target gene transcription. We report the… (More)
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