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NCOA3 wt Allele
Known as:
ACTR
, CAGH16
, p/CIP
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Human NCOA3 wild-type allele in the vicinity of 20q12 is approximately 155 kb in length. This allele, which encodes nuclear receptor coactivator 3…
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National Institutes of Health
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Related topics
Related topics
9 relations
20q12
CARM1 Transcription Regulation Pathway
Chromatin Remodeling Complex and Coactivator Pathway
Histone Acetylation
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Broader (1)
NCOA3 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Deregulated E2F and the AAA+ Coregulator ANCCA Drive Proto-Oncogene ACTR/AIB1 Overexpression in Breast Cancer
Elaine Y. C. Hsia
,
E. Kalashnikova
,
A. Revenko
,
J. Zou
,
A. Borowsky
,
Hong-Wu Chen
Molecular Cancer Research
2010
Corpus ID: 8057641
The proto-oncogene ACTR/AIB1, a coactivator for transcription factors such as the nuclear receptors and E2Fs, is frequently…
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Highly Cited
2006
Highly Cited
2006
The Activity and Stability of the Transcriptional Coactivator p/CIP/SRC-3 Are Regulated by CARM1-Dependent Methylation
Hina Naeem
,
Donghang Cheng
,
+4 authors
J. Torchia
Molecular and Cellular Biology
2006
Corpus ID: 25542045
ABSTRACT The transcriptional coactivator p/CIP(SRC-3/AIB1/ACTR/RAC3) binds liganded nuclear hormone receptors and facilitates…
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Highly Cited
2005
Highly Cited
2005
Generation and Characterization of Rac3 Knockout Mice
S. Corbetta
,
S. Gualdoni
,
+4 authors
I. de Curtis
Molecular and Cellular Biology
2005
Corpus ID: 23773998
ABSTRACT Rac proteins are members of the Rho family of GTPases involved in the regulation of actin dynamics. The three highly…
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Highly Cited
2005
Highly Cited
2005
Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells
P. Baugher
,
L. Krishnamoorthy
,
J. Price
,
S. Dharmawardhane
Breast Cancer Research
2005
Corpus ID: 8001277
IntroductionThe metastatic progression of cancer is a direct result of the disregulation of numerous cellular signaling pathways…
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Highly Cited
2004
Highly Cited
2004
Expression of the nuclear coactivator AIB1 in normal and malignant breast tissue
H. List
,
Ronald Reiter
,
Baljit Singh
,
A. Wellstein
,
A. Riegel
Breast Cancer Research and Treatment
2004
Corpus ID: 22245807
The gene of the nuclear receptor coactivator AIB1 (amplified in breast cancer 1) is amplified in breast cancer cell lines as well…
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Highly Cited
2003
Highly Cited
2003
The MN1 oncoprotein synergizes with coactivators RAC3 and p300 in RAR-RXR-mediated transcription
K. H. Wely
,
A. Molijn
,
+6 authors
E. Zwarthoff
Oncogene
2003
Corpus ID: 10105930
The t(12;22) creates an MN1–TEL fusion gene leading to acute myeloid leukemia. The fusion partner TEL (ETV6) is a member of the…
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Highly Cited
2001
Highly Cited
2001
AIB1 enhances estrogen-dependent induction of cyclin D1 expression.
M. Planas-Silva
,
Y. Shang
,
J. L. Donaher
,
M. Brown
,
R. Weinberg
Cancer research
2001
Corpus ID: 3234063
AIB1 was isolated as a gene amplified in breast cancer and encodes a protein that acts as a steroid receptor coactivator. The…
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Highly Cited
2001
Highly Cited
2001
An Isoform of the Coactivator AIB1 That Increases Hormone and Growth Factor Sensitivity Is Overexpressed in Breast Cancer*
Ronald Reiter
,
A. Wellstein
,
A. Riegel
The Journal of Biological Chemistry
2001
Corpus ID: 45913265
The AIB1 (amplified in breast cancer 1) protein is a coactivator that potentiates the transcriptional activity of nuclear hormone…
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Highly Cited
2000
Highly Cited
2000
Regulation of somatic growth by the p160 coactivator p/CIP.
Z. Wang
,
D. Rose
,
+10 authors
M. Rosenfeld
Proceedings of the National Academy of Sciences…
2000
Corpus ID: 24279423
A family of p160 coactivators was initially identified based on ligand-dependent interactions with nuclear receptors and thought…
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Highly Cited
2000
Highly Cited
2000
Amplification and over‐expression of the AIB1 nuclear receptor co‐activator gene in primary gastric cancers
C. Sakakura
,
A. Hagiwara
,
+8 authors
H. Yamagishi
International journal of cancer
2000
Corpus ID: 36699157
Our analysis of chromosomal aberrations in primary gastric cancers using comparative genomic hybridization has revealed novel…
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