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NCOA3 wt Allele

Known as: ACTR, CAGH16, p/CIP 
Human NCOA3 wild-type allele in the vicinity of 20q12 is approximately 155 kb in length. This allele, which encodes nuclear receptor coactivator 3… Expand
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
The transcriptional coactivator p/CIP(SRC-3/AIB1/ACTR/RAC3) binds liganded nuclear hormone receptors and facilitates… Expand
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Highly Cited
2005
Highly Cited
2005
Rac proteins are members of the Rho family of GTPases involved in the regulation of actin dynamics. The three highly homologous… Expand
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Highly Cited
2005
Highly Cited
2005
IntroductionThe metastatic progression of cancer is a direct result of the disregulation of numerous cellular signaling pathways… Expand
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2005
2005
Numerous studies indirectly implicate Rac GTPases in cancer. To investigate if Rac3 contributes to normal or malignant cell… Expand
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2003
2003
The t(12;22) creates an MN1–TEL fusion gene leading to acute myeloid leukemia. The fusion partner TEL (ETV6) is a member of the… Expand
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Highly Cited
2001
Highly Cited
2001
The gene of the nuclear receptor coactivator AIB1 (amplified in breast cancer 1) is amplified in breast cancer cell lines as well… Expand
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Highly Cited
2001
Highly Cited
2001
AIB1 was isolated as a gene amplified in breast cancer and encodes a protein that acts as a steroid receptor coactivator. The… Expand
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2001
2001
The AIB1 (amplified in breast cancer 1) protein is a coactivator that potentiates the transcriptional activity of nuclear hormone… Expand
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Highly Cited
2000
Highly Cited
2000
Our analysis of chromosomal aberrations in primary gastric cancers using comparative genomic hybridization has revealed novel… Expand
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Highly Cited
2000
Highly Cited
2000
A family of p160 coactivators was initially identified based on ligand-dependent interactions with nuclear receptors and thought… Expand
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