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NCK2 protein, human
Known as:
NCKBeta
, NCK adaptor protein 2, human
, NCK Adaptor Protein 2
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Encoded by human NCK2 Gene, ubiquitous 380-aa 43-kDa cytoplasmic NCK Adaptor Protein 2, containing 1 SH2 domain and 3 SH3 domains, associates with…
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National Institutes of Health
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Related topics
Related topics
10 relations
Broader (2)
Adaptor Proteins, Signal Transducing
Oncogene Proteins
Adaptor Signaling Protein Gene
Cell Proliferation
Cytoskeletal Modeling
NCK2 gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB‐induced Src phosphorylation and signaling
A. Georgakopoulos
,
C. Litterst
,
+4 authors
N. Robakis
The EMBO journal
2006
Corpus ID: 9074682
Bidirectional signaling triggered by interacting ephrinB receptors (EphB) and ephrinB ligands is crucial for development and…
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Highly Cited
2006
Highly Cited
2006
The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains*
S. Frese
,
W. Schubert
,
+4 authors
D. Heinz
Journal of Biological Chemistry
2006
Corpus ID: 12136869
Nck proteins are essential Src homology (SH) 2 and SH3 domain-bearing adapters that modulate actin cytoskeleton dynamics by…
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Highly Cited
2004
Highly Cited
2004
Wrch1 is a GTPase-deficient Cdc42-like protein with unusual binding characteristics and cellular effects.
J. Saras
,
P. Wollberg
,
P. Aspenström
Experimental cell research
2004
Corpus ID: 23212322
2004
2004
Tyr-298 in ephrinB1 is critical for an interaction with the Grb4 adaptor protein.
Y. Bong
,
Yeon-Hwa Park
,
Hyun-Shik Lee
,
K. Mood
,
A. Ishimura
,
I. Daar
The Biochemical journal
2004
Corpus ID: 26119881
The Eph family of receptor tyrosine kinases and their membrane-bound ligands, the ephrins, are thought to play a role in the…
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2001
2001
Identification and kinetic analysis of the interaction between Nck‐2 and DOCK180
Y. Tu
,
D. Kucik
,
C. Wu
FEBS letters
2001
Corpus ID: 31372015
Highly Cited
2000
Highly Cited
2000
Nckβ Adapter Regulates Actin Polymerization in NIH 3T3 Fibroblasts in Response to Platelet-Derived Growth Factor bb
Min Chen
,
H. She
,
A. Kim
,
D. Woodley
,
Wei Li
Molecular and Cellular Biology
2000
Corpus ID: 35086988
ABSTRACT The SH3-SH3-SH3-SH2 adapter Nck represents a two-gene family that includes Nckα (Nck) and Nckβ (Grb4/Nck2), and it links…
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Highly Cited
1999
Highly Cited
1999
Identification of Grb4/Nckβ, a Src Homology 2 and 3 Domain-containing Adapter Protein Having Similar Binding and Biological Properties to Nck*
Lara E. Braverman
,
L. Quilliam
The Journal of Biological Chemistry
1999
Corpus ID: 34853389
Adapter proteins made up of Src homology (SH) domains mediate multiple cellular signaling events initiated by receptor protein…
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Highly Cited
1998
Highly Cited
1998
Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways.
Y. Tu
,
F. Li
,
C. Wu
Molecular biology of the cell
1998
Corpus ID: 17144757
Many of the protein-protein interactions that are essential for eukaryotic intracellular signal transduction are mediated by…
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Highly Cited
1998
Highly Cited
1998
Grb10 Identified as a Potential Regulator of Growth Hormone (GH) Signaling by Cloning of GH Receptor Target Proteins*
S. Moutoussamy
,
F. Renaudie
,
F. Lago
,
P. Kelly
,
J. Finidori
The Journal of Biological Chemistry
1998
Corpus ID: 39690721
The cloning of receptor targets procedure, used so far to identify proteins associated with tyrosine kinase receptors was…
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Highly Cited
1998
Highly Cited
1998
Identification of Nck Family Genes, Chromosomal Localization, Expression, and Signaling Specificity*
Min Chen
,
H. She
,
+5 authors
Wei Li
The Journal of Biological Chemistry
1998
Corpus ID: 25646097
Already a dozen molecules share binding to the Src homology (SH) 3 domains of human Nck, an SH3-SH3-SH3-SH2 adapter protein. We…
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