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NCK2 gene

Known as: NCK-BETA, GRB4, NCK2 
This gene plays a role in signal transduction and is involved in cytoskeletal reorganization.
National Institutes of Health

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Related topics

6 relations
Cell ProliferationCytoskeletal ModelingNCK2 protein, humanSignal Transduction

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NCK2 wt Allele

Papers overview

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2019
2019
A Simple Competing Endogenous RNA Network Identifies Novel mRNA, miRNA, and lncRNA Markers in Human Cholangiocarcinoma
Background Cholangiocarcinoma (CCA) is the second most common malignant primary liver tumor and has shown an alarming increase in… 
Highly Cited
2016
Highly Cited
2016
Renal microRNA‐ and RNA‐profiles in progressive chronic kidney disease
MicroRNAs (miRNAs) contribute to chronic kidney disease (CKD) progression via regulating mRNAs involved in renal homeostasis… 
2015
2015
The Role of Misshapen NCK-related kinase (MINK), a Novel Ste20 Family Kinase, in the IRES-Mediated Protein Translation of Human Enterovirus 71
Human Enterovirus 71 (EV71) commonly causes Hand, Foot and Mouth Disease in young children, and occasional occurrences of… 
2011
2011
Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo
BackgroundNck1 and Nck2 adaptor proteins are involved in signaling pathways mediating proliferation, cytoskeleton organization… 
2010
2010
SKAP2, a novel target of HSF4b, associates with NCK2/F-actin at membrane ruffles and regulates actin reorganization in lens cell
In addition to roles in stress response, heat shock factors (HSFs) play crucial roles in differentiation and development. Heat… 
Highly Cited
2007
Highly Cited
2007
Differential regulation of WASP and N-WASP by Cdc42, Rac1, Nck, and PI(4,5)P2.
The Wiskott-Aldrich syndrome protein (WASP) and neural WASP (N-WASP) are key players in regulating actin cytoskeleton via the… 
Highly Cited
2006
Highly Cited
2006
Slit coordinates cardiac morphogenesis in Drosophila.
2006
2006
Solution Structure of the First Src Homology 3 Domain of Human Nck2
Highly Cited
2005
Highly Cited
2005
Analysis of differential gene expression in human melanocytic tumour lesions by custom made oligonucleotide arrays
Melanoma is one of the most aggressive types of cancer and resection of the tumour prior to dissemination of tumour cells is… 
1986
1986
Characterization of monoclonal antibodies directed against HLA class II molecules.
Four MAbs recognizing HLA class II antigens were produced by immunization with human leukemic cells, and were characterized… 
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